NFAT1 Antikörper (pSer330)

Produktnummer ABIN2839702

Produktdetails anti-NFAT1 Antikörper

Target: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Bindungsspezifität: pSer330

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFAT1 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NFATC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S330 of human NFATC2.

Klon: RB12881

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu NFAT1

Target: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Andere Bezeichnung: NFATC2 (NFAT1 Produkte)

Synonyme: NFATC2 antikoerper, AI607462 antikoerper, NF-ATc2 antikoerper, NFAT1 antikoerper, NFAT1-D antikoerper, Nfatp antikoerper, NFATP antikoerper, nuclear factor of activated T-cells 2 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 antikoerper, NFATC2 antikoerper, nfatc2 antikoerper, Nfatc2 antikoerper

Hintergrund: NFATC2 is a member of the nuclear factor of activated T cells (NFAT) family. It is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response.

Molekulargewicht: 100146

Gen-ID: 4773

NCBI Accession: NP_001129493, NP_036472, NP_775114

UniProt: Q13469

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, VEGF Signaling, BCR Signaling