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NFAT1 Produkte

(Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012].

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Ausgewählte NFAT1 Kategorien

NFAT1 Antikörper

High quality antibodies with extensive validation data.

NFAT1 ELISA Kits

Reliable ELISA kits for a wide range of species.

NFAT1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NFAT1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (7)
Kat. Nr. ABIN3017385
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IP
Validierungen
  • (2)
Kat. Nr. ABIN6972419
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN571020
Menge 100 μg
Datenblatt Datenblatt

Empfohlene NFAT1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6958239
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NFAT1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312443
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3094115
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3135265
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NFAT1 Produkten

Sun, Liu, Geng, Tao, Zheng, Wang, Fu, Wang, Xie, Zhang, Gong: "The elevated serum levels of calcineurin and nuclear factor of activated T-cells 1 in children with Kawasaki disease." in: Pediatric rheumatology online journal, Vol. 18, Issue 1, pp. 23, (2020) (PubMed).

Song, Carr, McDermott, Rodriguez, Babicheva, Balistrieri, Ayon, Wang, Makino, Yuan: "STIM2 (Stromal Interaction Molecule 2)-Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial Hypertension." in: Hypertension (Dallas, Tex. : 1979), Vol. 71, Issue 3, pp. 518-529, (2018) (PubMed).

Bai, Li, Wang, Lian, Wang: "The protective effects of PCPA against monocrotaline-induced pulmonary arterial hypertension are mediated through the downregulation of NFAT-1 and NF-κB." in: International journal of molecular medicine, Vol. 40, Issue 1, pp. 155-163, (2018) (PubMed).

Perotti, Baldassari, Molla, Vegetti, Bersani, Maurichi, Santinami, Anichini, Mortarini: "NFATc2 is an intrinsic regulator of melanoma dedifferentiation." in: Oncogene, Vol. 35, Issue 22, pp. 2862-72, (2016) (PubMed).

Liu, Han, Han, He: "Mesenchymal stem cell-conditioned media suppresses inflammation-associated overproliferation of pulmonary artery smooth muscle cells in a rat model of pulmonary hypertension." in: Experimental and therapeutic medicine, Vol. 11, Issue 2, pp. 467-475, (2016) (PubMed).

Quang, Leboucher, Passaro, Fuhrmann, Nourieh, Vincent-Salomon, Ghysdael: "The calcineurin/NFAT pathway is activated in diagnostic breast cancer cases and is essential to survival and metastasis of mammary cancer cells." in: Cell death & disease, Vol. 6, pp. e1658, (2015) (PubMed).

Scanlon, Banerjee, Inglehart, Liu, Russo, Hariharan, van Tubergen, Corson, Asangani, Mistretta, Chinnaiyan, DSilva: "Galanin modulates the neural niche to favour perineural invasion in head and neck cancer." in: Nature communications, Vol. 6, pp. 6885, (2015) (PubMed).

Cotroneo, Ashek, Wang, Wharton, Dubois, Bozorgi, Busbridge, Alavian, Wilkins, Zhao: "Iron homeostasis and pulmonary hypertension: iron deficiency leads to pulmonary vascular remodeling in the rat." in: Circulation research, Vol. 116, Issue 10, pp. 1680-90, (2015) (PubMed).

Lawrence, Borenstein-Auerbach, McGlynn, Kunnathodi, Shahbazov, Syed, Kanak, Takita, Levy, Naziruddin: "NFAT targets signaling molecules to gene promoters in pancreatic β-cells." in: Molecular endocrinology (Baltimore, Md.), Vol. 29, Issue 2, pp. 274-88, (2015) (PubMed).

Iampietro, Morissette, Gravel, Flamand: "Inhibition of interleukin-2 gene expression by human herpesvirus 6B U54 tegument protein." in: Journal of virology, Vol. 88, Issue 21, pp. 12452-63, (2014) (PubMed).

Synonyme und alternative Namen zu NFAT1

nuclear factor of activated T-cells 2 (NFATC2), nuclear factor of activated T-cells 2 (nfatc2), nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 (Nfatc2), nuclear factor of activated T-cells 2 (Nfatc2), AI607462, NF-ATc2, NFAT1, NFAT1-D, NFATC2, Nfatp, NFATP

Bezeichner auf Proteinebene für NFAT1

  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
  • nuclear factor of activated T-cells, cytoplasmic 2-like
  • NF-ATp
  • NFAT pre-existing subunit
  • T-cell transcription factor NFAT1
  • nuclear factor of activated T-cells, cytoplasmic 2
  • NF-ATc2
  • NFAT transcription complex, preexisting component
  • T cell transcription factor NFAT1
  • nuclear factor of activated T-cells, preexisting component
  • preexisting nuclear factor of activated T-cells 2
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