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NFASC Produkte

(Neurofascin (NFASC))
This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined.[provided by RefSeq, May 2009].

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Ausgewählte NFASC Kategorien

NFASC Antikörper

High quality antibodies with extensive validation data.

NFASC ELISA Kits

Reliable ELISA kits for a wide range of species.

NFASC Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene NFASC Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN727325
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (3)
Kat. Nr. ABIN3017267
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA
Validierungen
  • (2)
Kat. Nr. ABIN7191635
Menge 100 μL
Datenblatt Datenblatt

Empfohlene NFASC ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958098
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN2748418
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1144672
Menge 96 tests
Datenblatt Datenblatt

Empfohlene NFASC Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7197149
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1312436
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3084479
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren NFASC Produkten

Arrambide, Espejo, Eixarch, Villar, Alvarez-Cermeño, Picón, Kuhle, Disanto, Kappos, Sastre-Garriga, Pareto, Simon, Comabella, Río, Nos, Tur, Castilló, Vidal-Jordana, Galán, Arévalo, Auger, Rovira et al.: "Neurofilament light chain level is a weak risk factor for the development of MS. ..." in: Neurology, Vol. 87, Issue 11, pp. 1076-84, (2016) (PubMed).

OGuin, Gruber, Raine, Guzik, Poulos, Shafit-Zagardo: "Gas6 enhances axonal ensheathment by MBP+ membranous processes in human DRG/OL promyelinating co-cultures." in: ASN neuro, Vol. 6, Issue 1, pp. e00135, (2014) (PubMed).

Jones, Korobova, Svitkina: "Axon initial segment cytoskeleton comprises a multiprotein submembranous coat containing sparse actin filaments." in: The Journal of cell biology, Vol. 205, Issue 1, pp. 67-81, (2014) (PubMed).

Buffington, Sobotzik, Schultz, Rasband: "I?B? is not required for axon initial segment assembly." in: Molecular and cellular neurosciences, Vol. 50, Issue 1, pp. 1-9, (2012) (PubMed).

Dhaunchak, Becker, Schulman, De Faria, Rajasekharan, Banwell, Colman, Bar-Or: "Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis." in: Annals of neurology, Vol. 71, Issue 5, pp. 601-13, (2012) (PubMed).

Galiano, Jha, Ho, Zhang, Ogawa, Chang, Stankewich, Mohler, Rasband: "A distal axonal cytoskeleton forms an intra-axonal boundary that controls axon initial segment assembly." in: Cell, Vol. 149, Issue 5, pp. 1125-39, (2012) (PubMed).

Yap, Vakulenko, Kruczek, Motamedi, Digilio, Liu, Winckler: "Doublecortin (DCX) mediates endocytosis of neurofascin independently of microtubule binding." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 22, pp. 7439-53, (2012) (PubMed).

Cortes, Landis, Ottens: "High-capacity peptide-centric platform to decode the proteomic response to brain injury." in: Electrophoresis, Vol. 33, Issue 24, pp. 3712-9, (2012) (PubMed).

Shi, Sun, McBride, Cheng, Shi: "Acrolein induces myelin damage in mammalian spinal cord." in: Journal of neurochemistry, Vol. 117, Issue 3, pp. 554-64, (2011) (PubMed).

Roza, Castillejo, Lopez-García: "Accumulation of Kv7.2 channels in putative ectopic transduction zones of mice nerve-end neuromas." in: Molecular pain, Vol. 7, pp. 58, (2011) (PubMed).

Synonyme und alternative Namen zu NFASC

neurofascin (NFASC), neurofascin homolog (chicken) a (nfasca), neurofascin (Nfasc), AA387016, D430023G06Rik, mKIAA0756, NF, NRCAML, sc:d0205

Bezeichner auf Proteinebene für NFASC

  • neurofascin
  • neurofascin homolog
  • neurofascin homolog (chicken)
  • neurofascin-like
  • neurofascin homolog (chicken) isoform 1
  • neurofascin homolog (chicken) isoform 2
  • neurofascin homolog (chicken) isoform 3
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