Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Weitere Synonyme anzeigen
Human Polyclonal CADM1 Primary Antibody für ICC, IF - ABIN152528
Biederer, Sara, Mozhayeva, Atasoy, Liu, Kavalali, Südhof: SynCAM, a synaptic adhesion molecule that drives synapse assembly. in Science (New York, N.Y.) 2002
Show all 2 Pubmed References
Human Polyclonal CADM1 Primary Antibody für IF (p), IHC (p) - ABIN738351
Liu, Cui, Ao, Zhou, Zhou, Yuan, Xiang, Liu, Cao et al.: Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ... in Toxicology and applied pharmacology 2011
Show all 2 Pubmed References
Mammalian Monoclonal CADM1 Primary Antibody für ISt, IHC - ABIN1304990
Rollenhagen, Kuckuck, Ulm, Hartmann, Galuska, Geyer, Geyer, Mühlenhoff: Polysialylation of the synaptic cell adhesion molecule 1 (SynCAM 1) depends exclusively on the polysialyltransferase ST8SiaII in vivo. in The Journal of biological chemistry 2012
Human Polyclonal CADM1 Primary Antibody für IHC, ELISA - ABIN1585332
Ballester, Gonin, Rodenas, Bernaudin, Rouzier, Coutant, Daraï: Eutopic endometrium and peritoneal, ovarian and colorectal endometriotic tissues express a different profile of nectin-1, -3, -4 and nectin-like molecule 2. in Human reproduction (Oxford, England) 2012
High CADM1 expression is associated with KSHV infection.
the immunohistochemical expression of CADM1 has the potential to contribute as an auxiliary tool to the differential diagnosis between nevi and melanomas.
These findings suggest that CADM1 expression is a novel prognostic factor for peripheral T cell lymphoma, not otherwise specified
miR (zeige MLXIP Antikörper)-21 enhances chemo-resistance in tongue cancer cells via directly targeting CADM1, and an inverse correlation between miR (zeige MLXIP Antikörper)-21 and CADM1 expression in vivo. MiR (zeige MLXIP Antikörper)-21 overexpression is attributed to MYCN (zeige MYCN Antikörper)-mediated transcriptional regulation, which is also predictive for a worse prognosis in tongue cancer
We conclude that CADM1 was not associated with cell-cell interaction between lymphoma cells and macrophages, although CADM1 may be a useful marker of ATLL for diagnostic procedures.
miR (zeige MLXIP Antikörper)-21 overexpression promotes cardiac fibrosis via STAT3 (zeige STAT3 Antikörper) signaling pathway by decrease CADM1 expression, indicating miR (zeige MLXIP Antikörper)-21 as an important signaling molecule for cardiac fibrotic remodeling and atrial fibrillation.
Pathway analysis of the genes associated with the 46 CpG sites revealed an enrichment of immune system process genes, including LYST (zeige LYST Antikörper) (cg16962115, FDR = 1.24E-04), CADM1 (cg21933078, FDR = 1.22E-02) and NFATC1 (zeige NFATC1 Antikörper) (cg06784563, FDR = 1.46E-02)
CADM1 mRNA expression was highly upregulated in normal tissues compared to esophageal squamous cell carcinoma tissues, indicating that the loss of CADM1 expression influenced the pathogenesis, invasion, and metastasis of ESCC.
Eight and five of the nine samples were negative for cell adhesion molecule 1 and Osterix (zeige SP7 Antikörper) respectively. The other markers showed no statistical significance(CD151 (zeige CD151 Antikörper),ALP (zeige ALP Antikörper)). osteoblastic differentiation can occur in carcinoma cells and that cell adhesion molecule 1 could be a useful marker for identifying this phenomenon in carcinoma tissues
Our results suggest that, as in the CNS, CADM1 interactions drive exocytic site assembly and promote actin network formation. These results support the broader hypothesis that the effects of cell-cell contact on beta-cell maturation and function are mediated by the same extracellular protein interactions that drive the formation of the presynaptic exocytic machinery. These interactions may be therapeutic targets for re...
SynCAM1, Neuroligin-1B and Neuroligin-2A were overexpressed in newborn neurons in the dentate gyrus of 7- to 9-week-old mice. SynCAM1 increased the morphological maturation of dendritic spines and mossy fiber terminals while Neuroligin-1B increased spine density. In contrast, Neuroligin-2A increased both spine density and size as well as GABAergic innervation and resulted in a drastic increase of neuronal survival.
NF-kB mediated upregulation of CADM1 was identified as a mechanism of TNFalpha (zeige TNF Antikörper) induced migration.
The results of this study demonstrate that the synapse-organizing adhesion molecule (zeige NCAM1 Antikörper) SynCAM 1 has pronounced effects on neuronal connectivity in the hippocampal CA3 (zeige CA3 Antikörper) area.
Cadm1 is a direct target of NFATc1 (zeige NFATC1 Antikörper), which is induced by RANKL (zeige TNFSF11 Antikörper) through epigenetic modification, and regulates osteoclastic bone resorption in a negative feedback manner.
Data show that cell adhesion molecule 1 (SynCAM 1) generally prolongs the lifetime of spines.
This experiments show that the survival rate of adult-generated neurons is increased by overexpressing SynCAM 1
Our study reveals a novel mechanism of chronic NF-kappaB (zeige NFKB1 Antikörper) activation by CADM1 in HTLV-1 infected cells
Study demonstrates that polysialic acid-SynCAM 1 defines a subpopulation of NG2 (zeige Vcan Antikörper) cells and identifies the presence of polysialic acid-NRP2 (zeige NRP2 Antikörper) in microglia
CADM1 appeared to sustain gap junctional intercellular communication among alpha-cells via homophilic binding and, based on this action, CADM1 appears to prevent excessive secretion of glucagon (zeige GCG Antikörper) from alpha-cells.
This study demonistrated that SynCAM 1 in the synaptic organization of the rod visual pathway and provide evidence for novel roles of synaptic adhesion in the structural and functional integrity of ribbon synapses.
Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
, TSLC1/Nectin-like 2/IGSF4
, immunoglobulin superfamily member 4
, immunoglobulin superfamily, member 4
, immunoglobulin superfamily, member 4D variant 1
, immunoglobulin superfamily, member 4D variant 2
, nectin-like 2
, nectin-like protein 2
, spermatogenic immunoglobulin superfamily
, synaptic cell adhesion molecule
, truncated CADM1 protein
, tumor suppressor in lung cancer 1
, cell adhesion molecule 1
, cell adhesion molecule 1 transcript variant 8abc
, immunoglobulin superfamily member 4A
, immunosuperfamily protein Bl2
, immunoglobulin superfamily, member 4A
, secretory isoform of TSLC1
, tumor suppressor in lung cell-1