CADM1 Produkte
(Cell Adhesion Molecule 1 (CADM1))
Kategorien
Mediates homophilic cell-cell adhesion in a Ca(2+)- independent manner. Also mediates heterophilic cell-cell adhesion with CADM3 and PVRL3 in a Ca(2+)-independent manner. Acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. May contribute to the less invasive phenotypes of lepidic growth tumor cells. In mast cells, may mediate attachment to and promote communication with nerves. CADM1, together with MITF, is essential for development and survival of mast cells in vivo. May act as a synaptic cell adhesion molecule that drives synapse assembly. May be involved in neuronal migration, axon growth, pathfinding, and fasciculation on the axons of differentiating neurons. May play diverse roles in the spermatogenesis including in the adhesion of spermatocytes and spermatids to Sertoli cells and for their normal differentiation into mature spermatozoa.
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Ausgewählte CADM1 Kategorien
CADM1 Antikörper
High quality antibodies with extensive validation data.
CADM1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CADM1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CADM1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (5)
Kat. Nr.
ABIN565153
Menge
50 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (2)
- (3)
Kat. Nr.
ABIN738351
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6260400
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CADM1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954545
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6810493
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Competition ELISA
Validierungen
Kat. Nr.
ABIN2112203
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CADM1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (3)
Kat. Nr.
ABIN7274016
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7274017
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1347851
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CADM1 Produkten
: "Human T-cell leukemia virus type 1 (HTLV-1) tax requires CADM1/TSLC1 for inactivation of the NF-κB inhibitor A20 and constitutive NF-κB signaling." in: PLoS pathogens, Vol. 11, Issue 3, pp. e1004721, (2015) (PubMed).: "Docetaxel-loaded solid lipid nanoparticles suppress breast cancer cells growth with reduced myelosuppression toxicity." in: International journal of nanomedicine, Vol. 9, pp. 4829-46, (2014) (PubMed).
: "Polysialylation of the synaptic cell adhesion molecule 1 (SynCAM 1) depends exclusively on the polysialyltransferase ST8SiaII in vivo." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 35170-80, (2012) (PubMed).
: "Aberrant methylation accounts for cell adhesion-related gene silencing during 3-methylcholanthrene and diethylnitrosamine induced multistep rat lung carcinogenesis associated with overexpression of ..." in: Toxicology and applied pharmacology, Vol. 251, Issue 1, pp. 70-8, (2011) (PubMed).
: "Synaptic cell adhesion molecule SynCAM 1 is a target for polysialylation in postnatal mouse brain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 22, pp. 10250-5, (2010) (PubMed).
: "Cell adhesion molecule 1: a novel risk factor for venous thrombosis." in: Blood, Vol. 114, Issue 14, pp. 3084-91, (2009) (PubMed).
: "SMAGP, a new small trans-membrane glycoprotein altered in cancer." in: Oncogene, Vol. 23, Issue 19, pp. 3395-403, (2004) (PubMed).
: "SynCAM, a synaptic adhesion molecule that drives synapse assembly." in: Science (New York, N.Y.), Vol. 297, Issue 5586, pp. 1525-31, (2002) (PubMed).
Synonyme und alternative Namen zu CADM1
cell adhesion molecule 1 (CADM1), cell adhesion molecule 1 L homeolog (cadm1.L), cell adhesion molecule 1 (Cadm1), 2900073G06Rik, 3100001I08Rik, AI987920, BL2, bl2, Bl2, IGSF4, igsf4, Igsf4, IGSF4A, igsf4a, Igsf4a, Necl-2, necl-2, NECL2, necl2, Necl2, RA175, ra175, RA175A, RA175B, RA175C, RA175N, sgIGSF, sgigsf, SgIGSF, ST17, st17, sTSLC-1, stslc-1, SYNCAM, syncam, SynCam, synCAM1, syncam1, SynCAM1, TSLC1, tslc1, Tslc1, xnecl2Bezeichner auf Proteinebene für CADM1
- TSLC-1
- TSLC1/Nectin-like 2/IGSF4
- immunoglobulin superfamily member 4
- immunoglobulin superfamily, member 4
- immunoglobulin superfamily, member 4D variant 1
- immunoglobulin superfamily, member 4D variant 2
- nectin-like 2
- nectin-like protein 2
- spermatogenic immunoglobulin superfamily
- synaptic cell adhesion molecule
- truncated CADM1 protein
- tumor suppressor in lung cancer 1
- cell adhesion molecule 1
- NECL-2
- cell adhesion molecule 1 transcript variant 8abc
- immunoglobulin superfamily member 4A
- immunosuperfamily protein Bl2
- immunoglobulin superfamily, member 4A
- secretory isoform of TSLC1
- tumor suppressor in lung cell-1
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