ERK2 Protein (GST tag)

Produktnummer ABIN7533750

Produktdetails

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses ERK2 Protein ist gelabelt mit GST tag.

Verwendungszweck: Recombinant Human ERK2/MAPK1 Protein

Sequenz: MAAAAAAGAG PEMVRGQVFD VGPRYTNLSY IGEGAYGMVC SAYDNVNKVR VAIKKISPFE HQTYCQRTLR EIKILLRFRH ENIIGINDII RAPTIEQMKD VYIVQDLMET DLYKLLKTQH LSNDHICYFL YQILRGLKYI HSANVLHRDL KPSNLLLNTT CDLKICDFGL ARVADPDHDH TGFLTEYVAT RWYRAPEIML NSKGYTKSID IWSVGCILAE MLSNRPIFPG KHYLDQLNHI LGILGSPSQE DLNCIINLKA RNYLLSLPHK NKVPWNRLFP NADSKALDLL DKMLTFNPHK RIEVEQALAH PYLEQYYDPS DEPIAEAPFK FDMELDDLPK EKLKELIFEE TARFQPGYRS

Spezifität: Met1-Ser360

Reinheit: > 70 % by SDS-PAGE.

Biological Activity Comment: 1.Measured by its binding ability in a functional ELISA. Immobilized Human MAPK1 Protein at 1μg/mL (100 μL/well) can bind ERK1/2 Rabbit mAb with a linear range of 0.017-4.92 ng/mL.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/mL

Buffer: Supplied in 50 mM Tris,150 mM NaCl,0.1 mM EDTA,0.25 mM DTT,0.1 mM AEBSF,25 % glycerol,10 mM GSH, pH 8.0.

Konservierungsmittel: Dithiothreitol (DTT)

Vorsichtsmaßnahmen: This product contains Dithiothreitol (DTT): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -80 °C

Informationen zur Lagerung: This product is stable at ≤ -70° C for up to 1 year from the date of receipt.
For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature.

Antigendetails

Target: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Andere Bezeichnung: ERK2/MAPK1 (MAPK1 Produkte)

Synonyme: ERK-1 Protein, ERK1 Protein, ERT2 Protein, HS44KDAP Protein, HUMKER1A Protein, P44ERK1 Protein, P44MAPK Protein, PRKM3 Protein, p44-ERK1 Protein, p44-MAPK Protein, Erk-1 Protein, Erk1 Protein, Ert2 Protein, Esrk1 Protein, Mnk1 Protein, Mtap2k Protein, Prkm3 Protein, p44 Protein, p44erk1 Protein, p44mapk Protein, ERK Protein, ERK2 Protein, ERT1 Protein, MAPK2 Protein, P42MAPK Protein, PRKM1 Protein, PRKM2 Protein, p38 Protein, p40 Protein, p41 Protein, p41mapk Protein, 9030612K14Rik Protein, AA407128 Protein, AU018647 Protein, C78273 Protein, Erk2 Protein, Prkm1 Protein, p42mapk Protein, zERK2 Protein, MAPK1 Protein, Xp42 Protein, erk Protein, erk2 Protein, ert1 Protein, mapk Protein, mapk1b Protein, mapk2 Protein, mpk1 Protein, prkm1 Protein, prkm2 Protein, mapk1 Protein, mapk1a Protein, xp42 Protein, ATMPK1 Protein, F14N23.9 Protein, F14N23_9 Protein, MITOGEN-ACTIVATED PROTEIN KINASE Protein, mitogen-activated protein kinase 1 Protein, MNK1 Protein, ATMPK2 Protein, MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2 Protein, T30E16.13 Protein, T30E16_13 Protein, mitogen-activated protein kinase homolog 2 Protein, mitogen-activated protein kinase 3 Protein, mitogen-activated protein kinase 1 Protein, mitogen activated protein kinase 1 Protein, mitogen-activated protein kinase 1 L homeolog Protein, mitogen-activated protein kinase 1 S homeolog Protein, mitogen activated protein kinase 3 Protein, mitogen-activated protein kinase homolog 2 Protein, MAPK3 Protein, Mapk3 Protein, MAPK1 Protein, Mapk1 Protein, mapk1 Protein, mapk1.L Protein, mapk1.S Protein, PfMAP1 Protein, MPK1 Protein, PVX_084965 Protein, LOC9328617 Protein, Tsp_01601 Protein, MPK2 Protein

Hintergrund:

Description: ERK2 is a protein serine/threonine kinase, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions.

Name: ERK,ERK-2,ERK2,ERT1,MAPK2,P42MAPK,PRKM1,PRKM2,p38,p40,p41,p41mapk,p42-MAPK,MAPK1

Gen-ID: 5594

UniProt: P28482

Pathways: MAPK Signalweg, RTK Signalweg, Apoptose, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagie, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteine