NFKB1 Protein (His tag)

Produktnummer ABIN7319855

Produktdetails

Target: NFKB1 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses NFKB1 Protein ist gelabelt mit His tag.

Verwendungszweck: Recombinant Human NFKB1 (N-6His)

Sequenz: Met1-Gly434

Produktmerkmale: Recombinant Human Nuclear Factor NF-kappa-B P50 Subunit is produced by our E.coli expression system and the target gene encoding Met1-Gly434 is expressed with a 6His tag at the N-terminus.

Reinheit: >90 % as determined by reducing SDS-PAGE.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 20 mM GSH, pH 8.0.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: NFKB1 (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells 1 (NFKB1))

Andere Bezeichnung: NFKB1 (NFKB1 Produkte)

Synonyme: GKLP Protein, NKTL Protein, NTKL Protein, P105 Protein, TAPK Protein, TEIF Protein, TRAP Protein, EBP-1 Protein, KBF1 Protein, NF-kB1 Protein, NF-kappa-B Protein, NF-kappaB Protein, NFKB-p105 Protein, NFKB-p50 Protein, NFkappaB Protein, p105 Protein, p50 Protein, NF-kB Protein, NF-KB1 Protein, ebp-1 Protein, kbf1 Protein, nf-kappa-b Protein, nf-kappaB Protein, nfkb-p105 Protein, nfkb-p50 Protein, NF-kappaB1 Protein, p50/p105 Protein, BICDR-1 Protein, bicdr1 Protein, ccdc64 Protein, SCY1 like pseudokinase 1 Protein, nuclear factor kappa B subunit 1 Protein, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 L homeolog Protein, nuclear factor NF-kappa-B p105 subunit Protein, nucleoporin 107 Protein, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Protein, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 Protein, SCYL1 Protein, NFKB1 Protein, Nfkb1 Protein, nfkb1.L Protein, CpipJ_CPIJ012236 Protein, Nup107 Protein, nfkb1 Protein

Hintergrund:

Background: The 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene.

Synonym: DNA-binding factor KBF1, EBP-1, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

Molekulargewicht: 49.7 kDa

Pathways: p53 Signalweg, NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Toll-Like Receptors Cascades, BCR Signaling, S100 Proteine