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IKBKB Antikörper
IKBKB
Reaktivität: Human
ELISA, WB
Wirt: Maus
Monoclonal
10A2
unconjugated
Produktdetails anti-IKBKB Antikörper
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Target
Alle IKBKB Antikörper anzeigen
IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
Reaktivität
Alle Reaktivitäten für IKBKB Antikörper
Human
Wirt
Alle Wirte für IKBKB Antikörper
Maus
Klonalität
Alle Klonalitäten für IKBKB Antikörper
Monoklonal
Konjugat
Alle Konjugate für IKBKB Antikörper
Dieser IKBKB Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IKBKB Antikörper
ELISA, Western Blotting (WB)
Immunogen
IKBKB antibody was raised in Mouse using a purified recombinant fragment of IKBKB expressed in E. coli as the immunogen.
Klon
10A2
Isotyp
IgG1
Top Product
Discover our top product IKBKB Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1:10,000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Details zu IKBKB
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Target
IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
Andere Bezeichnung
IKBKB (IKBKB Produkte )
Synonyme
ikk-beta antikoerper, ikk2 antikoerper, ikkb antikoerper, ikkbeta antikoerper, IKBKB antikoerper, IKKB antikoerper, CG4201 antikoerper, DIK antikoerper, DLAK antikoerper, DmIKK antikoerper, DmIKKBeta antikoerper, DmIKKb antikoerper, DmIKKbeta antikoerper, DmIkkbeta antikoerper, Dmel\\CG4201 antikoerper, Dmikkb antikoerper, Dmikkbeta antikoerper, IK antikoerper, IKK antikoerper, IKK-beta antikoerper, IKKb antikoerper, IKKbeta antikoerper, IRD-5 antikoerper, IRD5 antikoerper, Ik antikoerper, Ikkb antikoerper, Ikkbeta antikoerper, Ird-5 antikoerper, Ird5 antikoerper, LRK antikoerper, Lak antikoerper, anon-89Bd antikoerper, dIKK antikoerper, dIKK-beta antikoerper, dIKKbeta antikoerper, dLak antikoerper, dmIKKbeta antikoerper, ikk antikoerper, ird antikoerper, ird5/DmIkk[beta] antikoerper, IKK2 antikoerper, NFKBIKB antikoerper, AIM-1 antikoerper, AI132552 antikoerper, IKK-2 antikoerper, IKK[b] antikoerper, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta L homeolog antikoerper, inhibitor of nuclear factor kappa B kinase subunit beta antikoerper, I-kappaB kinase beta antikoerper, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta antikoerper, inhibitor of kappaB kinase beta antikoerper, ikbkb.L antikoerper, IKBKB antikoerper, ikbkb antikoerper, IKKbeta antikoerper, Ikbkb antikoerper
Hintergrund
IKBKB is a member of the IKK complex which is composed of IKK-alpha, IKK-beta, IKK-gamma and IKAP. Phosphorylation of I-Kappa-B on a serine residue by the IKK complex frees NF-kB from I-Kappa-B and marks it for degradation via ubiquination. IKK-beta has been shown to activate NF-kB and phosphorylate IKB-alpha and beta. Phosphorylation of 2 sites at the activation loop of IKK-beta is essential for activation of IKK by TNF and IL1. Once activated, IKK-beta autophosphorylates which in turn decreases IKK activity and prevents prolonged activation of the inflammatory response. Additionally, IKK-beta activity can also be regulated by MEKK-1. Synonyms: Monoclonal IKBKB antibody, Anti-IKBKB antibody, Inhibitor of kappa light polypeptide gene enhancer in B-cells antibody, Kinase beta antibody, IKK2 antibody, IKKB antibody.
Pathways
NF-kappaB Signalweg , RTK Signalweg , T-Zell Rezeptor Signalweg , TLR Signalweg , Fc-epsilon Rezeptor Signalübertragung , Neurotrophin Signalübertragung , Activation of Innate immune Response , Production of Molecular Mediator of Immune Response , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteine
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