GSK3 beta Antikörper (C-Term)

Produktnummer ABIN7529527

Produktdetails anti-GSK3 beta Antikörper

Target: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSK3 beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: GSK3β Rabbit pAb

Sequenz: PWTKVFRPRT PPEAIALCSR LLEYTPTARL TPLEACAHSF FDELRDPNVK LPNGRDTPAL FNFTTQELSS NPPLATILIP PHARIQAAAS TPTNATAASD ANTGDRGQTN NAASASASNS T

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human GSK3beta (NP_001139628.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GSK3 beta

Target: GSK3 beta (GSK3b) (Glycogen Synthase Kinase 3 beta (GSK3b))

Andere Bezeichnung: GSK3B (GSK3b Produkte)

Synonyme: GSK3 antikoerper, GSK-3 antikoerper, C86142 antikoerper, GSK-3beta antikoerper, 7330414F15Rik antikoerper, 8430431H08Rik antikoerper, GSK3beta antikoerper, fk80d11 antikoerper, GSK-3[b] antikoerper, wu:fb68h05 antikoerper, wu:fk80d11 antikoerper, gsk-3 antikoerper, gsk3 antikoerper, gsk3-beta antikoerper, gsk3beta antikoerper, xgsk-3 antikoerper, glycogen synthase kinase 3 beta antikoerper, glycogen synthase kinase 3 beta L homeolog antikoerper, GSK3B antikoerper, Gsk3b antikoerper, gsk3b antikoerper, gsk3b.L antikoerper

Hintergrund: The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,GSK3B,gsk-3β,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Regulation of eIF2,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Cell Cycle,Centrosome,G1/S Checkpoint,Cell Adhesion,Microtubules,Hedgehog Signaling Pathway,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Carbohydrate metabolism,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Immunology & Inflammation,B Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neurodegenerative Diseases Markers,Other Neurological disorders,Stem Cells,Cardiovascular,Heart,Hypertrophy,Akt downstream targets,GSK3B

Molekulargewicht: 46kDa/48kDa

Gen-ID: 2932

UniProt: P49841

Pathways: WNT Signalweg, Hedgehog Signalweg, Fc-epsilon Rezeptor Signalübertragung, Cellular Glucan Metabolic Process, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Autophagie, BCR Signaling, Warburg Effekt