MAP3K7 Antikörper (pThr187)
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- Target Alle MAP3K7 Antikörper anzeigen
- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
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Bindungsspezifität
- pThr187
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MAP3K7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Produktmerkmale
- Phosphorylated antibody
- Aufreinigung
- Affinity purification
- Immunogen
- Synthesized peptide derived from human Tak1 around the phosphorylation site of Thr187
- Isotyp
- IgG
- Top Product
- Discover our top product MAP3K7 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
- Andere Bezeichnung
- MAP3K7 (MAP3K7 Produkte)
- Synonyme
- si:ch211-225h9.1 antikoerper, zgc:110612 antikoerper, Tak1 antikoerper, MEKK7 antikoerper, TAK1 antikoerper, TGF1a antikoerper, B430101B05 antikoerper, C87327 antikoerper, mitogen-activated protein kinase kinase kinase 7 antikoerper, mitogen activated protein kinase kinase kinase 7 antikoerper, map3k7 antikoerper, Map3k7 antikoerper, MAP3K7 antikoerper
- Hintergrund
- Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
- Molekulargewicht
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Observed_MW: 60 kDa
Calculated_MW: 67 kDa
- UniProt
- O43318
- Pathways
- NF-kappaB Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
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