MAP3K7 Antikörper (AA 471-579)
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- Target Alle MAP3K7 Antikörper anzeigen
- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
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Bindungsspezifität
- AA 471-579
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MAP3K7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human MAP3K7 (AA: 471-579) expressed in E. coli.
- Klon
- 3E8H4
- Isotyp
- IgG2a
- Top Product
- Discover our top product MAP3K7 Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: , ICC: , FCM:
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide and 0.5 % protein stabilizer
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- MAP3K7 (Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7))
- Andere Bezeichnung
- MAP3K7 (MAP3K7 Produkte)
- Synonyme
- si:ch211-225h9.1 antikoerper, zgc:110612 antikoerper, Tak1 antikoerper, MEKK7 antikoerper, TAK1 antikoerper, TGF1a antikoerper, B430101B05 antikoerper, C87327 antikoerper, mitogen-activated protein kinase kinase kinase 7 antikoerper, mitogen activated protein kinase kinase kinase 7 antikoerper, map3k7 antikoerper, Map3k7 antikoerper, MAP3K7 antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2, this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.,
Aliases: TAK1, MEKK7, TGF1a
- Molekulargewicht
- 67.2 kDa
- Gen-ID
- 6885
- HGNC
- 6885
- Pathways
- NF-kappaB Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway
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