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IKBKB Antikörper (AA 630-730)
IKBKB
Reaktivität: Human
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN3022876
Produktdetails anti-IKBKB Antikörper
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Target
Alle IKBKB Antikörper anzeigen
IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
Bindungsspezifität
Alle Epitope für IKBKB Antikörper
AA 630-730
Reaktivität
Alle Reaktivitäten für IKBKB Antikörper
Human
Wirt
Alle Wirte für IKBKB Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für IKBKB Antikörper
Polyklonal
Konjugat
Alle Konjugate für IKBKB Antikörper
Dieser IKBKB Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IKBKB Antikörper
Western Blotting (WB), Immunohistochemistry (IHC)
Sequenz
EEVVSLMNED EKTVVRLQEK RQKELWNLLK IACSKVRGPV SGSPDSMNAS RLSQPGQLMS QPSTASNSLP EPAKKSEELV AEAHNLCTLL ENAIQDTVRE Q
Kreuzreaktivität
Human, Maus, Ratte
Produktmerkmale
Polyclonal Antibodies
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 630-730 of human IKKbeta (NP_001547.1).
Isotyp
IgG
Alternativen
(anzeigen)
Anwendungsinformationen
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Applikationshinweise
WB,1:500 - 1:2000,IHC,1:50 - 1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid freeze / thaw cycles
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Referenzen für anti-IKBKB Antikörper (ABIN3022876)
(ausblenden)
Wang, Wang, Liu, Wang, Xu, Liu, Zhu, Chen, Situ, Lin : "Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages. " in: International journal of molecular medicine , Vol. 41 , Issue 1 , pp. 340-352 , (2018 ) (PubMed ).
Gao, Yang, Yuan, Huang, Xu, Mao, Yuan, Bi : "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration. " in: Oncogenesis , Vol. 6 , Issue 9 , pp. e383 , (2017 ) (PubMed ).
Details zu IKBKB
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Target
IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))
Andere Bezeichnung
IKBKB (IKBKB Produkte )
Synonyme
ikk-beta antikoerper, ikk2 antikoerper, ikkb antikoerper, ikkbeta antikoerper, IKBKB antikoerper, IKKB antikoerper, CG4201 antikoerper, DIK antikoerper, DLAK antikoerper, DmIKK antikoerper, DmIKKBeta antikoerper, DmIKKb antikoerper, DmIKKbeta antikoerper, DmIkkbeta antikoerper, Dmel\\CG4201 antikoerper, Dmikkb antikoerper, Dmikkbeta antikoerper, IK antikoerper, IKK antikoerper, IKK-beta antikoerper, IKKb antikoerper, IKKbeta antikoerper, IRD-5 antikoerper, IRD5 antikoerper, Ik antikoerper, Ikkb antikoerper, Ikkbeta antikoerper, Ird-5 antikoerper, Ird5 antikoerper, LRK antikoerper, Lak antikoerper, anon-89Bd antikoerper, dIKK antikoerper, dIKK-beta antikoerper, dIKKbeta antikoerper, dLak antikoerper, dmIKKbeta antikoerper, ikk antikoerper, ird antikoerper, ird5/DmIkk[beta] antikoerper, IKK2 antikoerper, NFKBIKB antikoerper, AIM-1 antikoerper, AI132552 antikoerper, IKK-2 antikoerper, IKK[b] antikoerper, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta L homeolog antikoerper, inhibitor of nuclear factor kappa B kinase subunit beta antikoerper, I-kappaB kinase beta antikoerper, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta antikoerper, inhibitor of kappaB kinase beta antikoerper, ikbkb.L antikoerper, IKBKB antikoerper, ikbkb antikoerper, IKKbeta antikoerper, Ikbkb antikoerper
Hintergrund
The protein encoded by this gene phosphorylates the inhibitor in the inhibitor/NF-kappa-B complex, causing dissociation of the inhibitor and activation of NF-kappa-B. The encoded protein itself is found in a complex of proteins. Several transcript variants, some protein-coding and some not, have been found for this gene.,IKBKB,IKK-beta,IKK2,IKKB,IMD15,NFKBIKB,IKK beta,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Death Receptor Signaling Pathway,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,IKBKB
Molekulargewicht
29 kDa/79 kDa/85 kDa/86 kDa
Gen-ID
3551
UniProt
O14920
Pathways
NF-kappaB Signalweg , RTK Signalweg , T-Zell Rezeptor Signalweg , TLR Signalweg , Fc-epsilon Rezeptor Signalübertragung , Neurotrophin Signalübertragung , Activation of Innate immune Response , Production of Molecular Mediator of Immune Response , Hepatitis C , Toll-Like Receptors Cascades , BCR Signaling , Ubiquitin Proteasome Pathway , S100 Proteine
Zuletzt angesehen
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