RIPK1 Antikörper (AA 17-289)

Produktnummer ABIN1870364

Produktdetails anti-RIPK1 Antikörper

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Bindungsspezifität: AA 17-289

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RIPK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Verwendungszweck: Polyclonal Antibody to Receptor Interacting Serine Threonine Kinase 1 (RIPK1)

Spezifität: The antibody is a rabbit polyclonal antibody raised against RIPK1. It has been selected for its ability to recognize RIPK1 in immunohistochemical staining and western blotting.

Aufreinigung: Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Immunogen: Recombinant Receptor Interacting Serine Threonine Kinase 1 (RIPK1) corresdonding to Phe17~Tyr289 with N-terminal His Tag

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Western blotting: 0.5-3 μg/mL

Immunohistochemistry: 5-30 μg/mL

Immunocytochemistry: 5-30 μg/mL

Optimal working dilutions must be determined by end user.

Kommentare:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 24 months

Details zu RIPK1

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Abstract: RIPK1 Produkte

Synonyme: RIP antikoerper, RIP1 antikoerper, D330015H01Rik antikoerper, Rinp antikoerper, Rip1 antikoerper, rip1 antikoerper, ripk1 antikoerper, xRIP1beta antikoerper, xrip1 antikoerper, receptor interacting serine/threonine kinase 1 antikoerper, receptor (TNFRSF)-interacting serine-threonine kinase 1 antikoerper, receptor interacting serine/threonine kinase 1 L homeolog antikoerper, RIPK1 antikoerper, Ripk1 antikoerper, ripk1.L antikoerper

Hintergrund: RIP, Receptor-Interacting Protein, Cell death protein RIP, Serine/threonine-protein kinase RIP

Pathways: NF-kappaB Signalweg, Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interaktom, Ubiquitin Proteasome Pathway