RIPK1 Produkte
(Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))
Kategorien
Serine-threonine kinase which transduces inflammatory and cell-death signals (necroptosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necroptosis-inducing complex.
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Ausgewählte RIPK1 Kategorien
RIPK1 Antikörper
High quality antibodies with extensive validation data.
RIPK1 ELISA Kits
Reliable ELISA kits for a wide range of species.
RIPK1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene RIPK1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7441202
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7441205
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, IF
Validierungen
- (6)
Kat. Nr.
ABIN6146959
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene RIPK1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6959056
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969845
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969846
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene RIPK1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN1318108
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124799
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1318110
Menge
2 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren RIPK1 Produkten
: "Isolation and characterization of cluster of differentiation 9-positive ependymal cells as potential adult neural stem/progenitor cells in the third ventricle of adult rats." in: Cell and tissue research, Vol. 379, Issue 3, pp. 497-509, (2020) (PubMed).: "Modulation of lung cancer cell plasticity and heterogeneity with the restoration of cisplatin sensitivity by neurotensin antibody." in: Cancer letters, Vol. 444, pp. 147-161, (2019) (PubMed).
: "Silencing of A20 Aggravates Neuronal Death and Inflammation After Traumatic Brain Injury: A Potential Trigger of Necroptosis." in: Frontiers in molecular neuroscience, Vol. 12, pp. 222, (2019) (PubMed).
: "Necroptosis in pulmonary macrophages mediates lipopolysaccharide-induced lung inflammatory injury by activating ZBP-1." in: International immunopharmacology, Vol. 77, pp. 105944, (2019) (PubMed).
: "Transcription modulation by CDK9 regulates inflammatory genes and RIPK3-MLKL-mediated necroptosis in periodontitis progression." in: Scientific reports, Vol. 9, Issue 1, pp. 17369, (2019) (PubMed).
: "TDP-43 accelerates age-dependent degeneration of interneurons." in: Scientific reports, Vol. 7, Issue 1, pp. 14972, (2018) (PubMed).
: "Targeting necroptotic cell death pathway by high-intensity interval training (HIIT) decreases development of post-ischemic adverse remodelling after myocardial ischemia / reperfusion injury." in: Journal of cell communication and signaling, (2018) (PubMed).
: "Vascular peroxide 1 promotes ox-LDL-induced programmed necrosis in endothelial cells through a mechanism involving β-catenin signaling." in: Atherosclerosis, Vol. 274, pp. 128-138, (2018) (PubMed).
: "Bifidobacterial recombinant thymidine kinase-ganciclovir gene therapy system induces FasL and TNFR2 mediated antitumor apoptosis in solid tumors." in: BMC cancer, Vol. 16, pp. 545, (2017) (PubMed).
: "Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis." in: Cell death & disease, Vol. 7, Issue 6, pp. e2287, (2016) (PubMed).
Synonyme und alternative Namen zu RIPK1
receptor interacting serine/threonine kinase 1 (RIPK1), receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1), receptor interacting serine/threonine kinase 1 (Ripk1), receptor interacting serine/threonine kinase 1 L homeolog (ripk1.L), D330015H01Rik, Rinp, RIP, RIP1, Rip1, rip1, ripk1, xrip1, xRIP1betaBezeichner auf Proteinebene für RIPK1
- RIP-1
- cell death protein RIP
- receptor interacting protein
- receptor-interacting protein 1
- receptor-interacting serine/threonine-protein kinase 1
- serine/threonine-protein kinase RIP
- receptor (TNFRSF)-interacting serine-threonine kinase 1
- receptor interacting serine/threonine kinase 1 L homeolog
- receptor-interacting protein 1 beta
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