MAPK10 Protein (His tag)

Produktnummer ABIN2725411

Produktdetails

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses MAPK10 Protein ist gelabelt mit His tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human MAPK10 (full length, N-term HIS tag, transcript variant 4) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the N-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Andere Bezeichnung: Mapk10 (MAPK10 Produkte)

Synonyme: MAPK10 Protein, zgc:123234 Protein, DKFZp459H0638 Protein, Jnk3 Protein, SAPKC Protein, SAPb Protein, Serk2 Protein, JNK3 Protein, JNK3A Protein, PRKM10 Protein, SAPK1b Protein, p493F12 Protein, p54bSAPK Protein, C230008H04Rik Protein, JNK3B1 Protein, JNK3B2 Protein, SAPK(beta) Protein, ATMPK10 Protein, MAP kinase 10 Protein, mitogen-activated protein kinase 8 S homeolog Protein, mitogen-activated protein kinase 10 Protein, mitogen activated protein kinase 10 Protein, MAP kinase 10 Protein, mapk8.S Protein, MAPK10 Protein, mapk10 Protein, Mapk10 Protein, MPK10 Protein

Hintergrund: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Molekulargewicht: 31.8 kDa

NCBI Accession: NP_620447

Pathways: MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades