MAPK10 Produkte
(Mitogen-Activated Protein Kinase 10 (MAPK10))
Kategorien
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This protein is a neuronal-specific form of c-Jun N-terminal kinases (JNKs). Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways during neuronal apoptosis. Beta-arrestin 2, a receptor-regulated MAP kinase scaffold protein, is found to interact with, and stimulate the phosphorylation of this kinase by MAP kinase kinase 4 (MKK4). Cyclin-dependent kianse 5 can phosphorylate, and inhibit the activity of this kinase, which may be important in preventing neuronal apoptosis. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].
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Ausgewählte MAPK10 Kategorien
MAPK10 Antikörper
High quality antibodies with extensive validation data.
MAPK10 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MAPK10 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, IHC, ICC, FACS
Validierungen
- (4)
Kat. Nr.
ABIN5542487
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (4)
Kat. Nr.
ABIN3022948
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), ICC, IHC (fro)
Validierungen
- (3)
Kat. Nr.
ABIN7429106
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene MAPK10 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6213165
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene MAPK10 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1310260
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (2)
Kat. Nr.
ABIN5570193
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (2)
Kat. Nr.
ABIN5570531
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MAPK10 Produkten
: "EphrinB2 controls vessel pruning through STAT1-JNK3 signalling." in: Nature communications, Vol. 6, pp. 6576, (2015) (PubMed).: "JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis." in: PLoS ONE, Vol. 9, Issue 1, pp. e87067, (2014) (PubMed).
: "Tumor necrosis factor-alpha-elicited stimulation of gamma-secretase is mediated by c-Jun N-terminal kinase-dependent phosphorylation of presenilin and nicastrin." in: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4201-12, (2008) (PubMed).
: "The lectin jacalin induces phosphorylation of ERK and JNK in CD4+ T cells." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 682-8, (2003) (PubMed).
: "Role of mitogen- and stress-activated kinases in ischemic injury." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 22, Issue 6, pp. 631-47, (2002) (PubMed).
: "Head-to-head juxtaposition of Fas-associated phosphatase-1 (FAP-1) and c-Jun NH2-terminal kinase 3 (JNK3) genes: genomic structure and seven polymorphisms of the FAP-1 gene." in: Journal of human genetics, Vol. 47, Issue 11, pp. 614-9, (2002) (PubMed).
: "Cyclin-dependent kinase 5 prevents neuronal apoptosis by negative regulation of c-Jun N-terminal kinase 3." in: The EMBO journal, Vol. 21, Issue 3, pp. 324-33, (2002) (PubMed).
: "gp120-mediated induction of the MAPK cascade is dependent on the activation state of CD4(+) lymphocytes." in: Blood, Vol. 100, Issue 7, pp. 2546-53, (2002) (PubMed).
: "Mitogen-activated protein kinase kinase 4 (MKK4)." in: The international journal of biochemistry & cell biology, Vol. 32, Issue 6, pp. 581-7, (2000) (PubMed).
: "Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3." in: Science (New York, N.Y.), Vol. 290, Issue 5496, pp. 1574-7, (2000) (PubMed).
Synonyme und alternative Namen zu MAPK10
mitogen-activated protein kinase 8 S homeolog (mapk8.S), mitogen-activated protein kinase 10 (MAPK10), mitogen-activated protein kinase 10 (mapk10), mitogen activated protein kinase 10 (Mapk10), mitogen-activated protein kinase 10 (Mapk10), MAP kinase 10 (MPK10), ATMPK10, C230008H04Rik, DKFZp459H0638, Jnk3, JNK3, JNK3A, JNK3B1, JNK3B2, MAPK10, MAP kinase 10, p54bSAPK, p493F12, PRKM10, SAPb, SAPK(beta), SAPK1b, SAPKC, Serk2, zgc:123234Bezeichner auf Proteinebene für MAPK10
- mitogen-activated protein kinase 10
- jnk3
- MAP kinase 10
- MAPK 10
- SAPK-beta
- Stress activated protein kinase beta
- c-Jun N-terminal kinase 3
- p54-beta
- stress-activated protein kinase JNK3
- JNK3 alpha protein kinase
- MAP kinase p49 3F12
- stress activated protein kinase beta
- stress-activated protein kinase 1b
- JNK3 beta1 protein kinase
- JNK3 beta2 protein kinase
- SAPK/Erk/kinase 2
- mitogen activated protein kinase 10
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