MAPKAP Kinase 5 Produkte
(Mitogen-Activated Protein Kinase-Activated Protein Kinase 5 (MAPKAPK5))
Kategorien
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012].
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Ausgewählte MAPKAP Kinase 5 Kategorien
MAPKAP Kinase 5 Antikörper
High quality antibodies with extensive validation data.
MAPKAP Kinase 5 ELISA Kits
Reliable ELISA kits for a wide range of species.
MAPKAP Kinase 5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene MAPKAP Kinase 5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Applikation
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
- (3)
Kat. Nr.
ABIN710546
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p)
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN389587
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN969362
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene MAPKAP Kinase 5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380844
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene MAPKAP Kinase 5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (2)
Kat. Nr.
ABIN1310330
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5569672
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (2)
Kat. Nr.
ABIN5570546
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren MAPKAP Kinase 5 Produkten
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).: "Abrogation of microcystin cytotoxicity by MAP kinase inhibitors and N-acetyl cysteine is confounded by OATPIB1 uptake activity inhibition." in: Toxicon : official journal of the International Society on Toxinology, Vol. 55, Issue 4, pp. 827-37, (2010) (PubMed).
: "Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs." in: Science signaling, Vol. 2, Issue 94, pp. ra69, (2009) (PubMed).
: "PRAK is essential for ras-induced senescence and tumor suppression." in: Cell, Vol. 128, Issue 2, pp. 295-308, (2007) (PubMed).
: "p38 mitogen-activated protein kinase (MAPK) first regulates filamentous actin at the 8-16-cell stage during preimplantation development." in: Biology of the cell / under the auspices of the European Cell Biology Organization, Vol. 97, Issue 8, pp. 629-40, (2005) (PubMed).
: "Effect of different dietary ideal protein concentrations on broiler performance." in: British poultry science, Vol. 45, Issue 4, pp. 504-11, (2004) (PubMed).
: "Regulation of PRAK subcellular location by p38 MAP kinases." in: Molecular biology of the cell, Vol. 14, Issue 6, pp. 2603-16, (2003) (PubMed).
: "p62 functions as a p38 MAP kinase regulator." in: Biochemical and biophysical research communications, Vol. 269, Issue 2, pp. 521-5, (2000) (PubMed).
Synonyme und alternative Namen zu MAPKAP Kinase 5
mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), mitogen-activated protein kinase-activated protein kinase 5 (mapkapk5), MAP kinase-activated protein kinase 5 (Mapkapk5), mitogen-activated protein kinase-activated protein kinase 5 (Mapkapk5), MAPKAP-K5, MAPKAPK5, MK-5, MK5, PRAKBezeichner auf Proteinebene für MAPKAP Kinase 5
- mitogen-activated protein kinase-activated protein kinase 5
- MAP kinase-activated protein kinase 5
- MAP kinase-activated protein kinase 5-like
- MAPK-activated protein kinase 5
- MAPKAP kinase 5
- MAPKAPK-5
- p38-regulated/activated protein kinase
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