IL12 Protein

Produktnummer ABIN1112288

Produktdetails

Target: IL12 (Interleukin 12 (IL12))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Biochemical Assay (BCA)

Sequenz: p35 Subunit: RNLPVATPDP GMFPCLHHSQ NLLRAVSNML QKARQTLEFY PCTSEEIDHE DITKDKTSTV EACLPLELTK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLSSIYEDLK MYQVEFKTMN AKLLMDPKRQ IFLDQNMLAV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNASp40 Subunit: IWELKKDVYV VELDWYPDAP GEMVVLTCDT PEEDGITWTL DQSSEVLGSG KTLTIQVKEF GDAGQYTCHK GGEVLSHSLL LLHKKEDGIW STDILKDQKE PKNKTFLRCE AKNYSGRFTC WWLTTISTDL TFSVKSSRGS SDPQGVTCGA ATLSAERVRG DNKEYEYSVE CQEDSACPAA EESLPIEVMV DAVHKLYENY TSSFFIRDII KPDPPKNLQL KPLKNSRQVE VSWEYPDTWS TPHSYFSLTF CVQVQGKSKR EKKDRVFTDK TSATVICRKN ASISVRAQDR YYSSSWSEWA SVPCS.

Keine Kreuzreaktivität: Maus, Affe, Bakterien

Produktmerkmale: The ED50 was determined by the induction of IFN-gamma from NK cells co-stimulated with IL-18 is less or equal to 1.0 ng/ml, corresponding to a specific activity of greater than or equal to 1 x 10^6 units/mg.

Reinheit: > 95 % as determined by SDS-PAGE analysis.

Sterilität: 0.2 μm filtered

Endotoxin-Niveau: Endotoxin: 1.EU/µg determined by LAL method.

Anwendungsinformationen

Kommentare:

Length: 503 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: We recommended spin the vial shortly prior to opening to bring the contents to the bottom. Lyophilized hIL12 should be reconstituted in deionized water to 0,1-1 µg/mL to regain full activity. These stock solutions should be apportioned into working aliquots and stored at -20 °C. Further dilutions should be made in low endotoxin medium or buffered solution with FBS or tissue culture grade BSA.

Lagerung: -20 °C

Antigendetails

Target: IL12 (Interleukin 12 (IL12))

Andere Bezeichnung: IL-12 (IL12 Produkte)

Synonyme: CLMF Protein, CLMF2 Protein, IL-12B Protein, NKSF Protein, NKSF2 Protein, p40 Protein, Il-12b Protein, Il12p40 Protein, Il-12p40 Protein, Il12 Protein, IL-12p40 Protein, IL-12 Protein, LOC100217488 Protein, IL-12p35 Protein, Il-12a Protein, Ll12a Protein, p35 Protein, IL12p40 Protein, IL12B Protein, IL-12 p35 Protein, interleukin 12B Protein, interleukin 12A Protein, interleukin 12b Protein, interleukin 12a Protein, Interleukin 12 level Protein, IL12B Protein, IL12A Protein, Il12b Protein, Il12a Protein, IL12 Protein, il12a Protein

Molekulargewicht: 75 kDa.

Pathways: JAK-STAT Signalweg, TLR Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome