Cancer Immune Checkpoints
Cancer Immune Checkpoints
Inhibitory T-Cell Receptors
TIM 3 - TIM3
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be...
LAG3 - Lymphocyte-Activation Gene 3
Lymphocyte-activation protein 3 belongs to Ig superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The...
VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation):
Immunoregulatory receptor which inhibits the T-cell response (PMID: 24691993). May promote differentiation of embryonic stem cells, by inhibiting...
TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains):
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several...
BTLA (B and T Lymphocyte Associated):
This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor...
TNFRSF14 - HVEM
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor was identified as a cellular mediator of herpes simplex...
| KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3): | KIR2DL3 Antikörper | KIR2DL3 ELISA Kits | KIR2DL3 Proteine |
| TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4): | TIMD4 Antikörper | TIMD4 ELISA Kits | TIMD4 Proteine |
| TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14): | TNFSF14 Antikörper | TNFSF14 ELISA Kits | TNFSF14 Proteine |
Major Histocompatibility Complex
HLA-A (Major Histocompatibility Complex, Class I, A):
HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is...
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MR1 (Major Histocompatibility Complex, Class I-Related):
non-MHC-linked class I-related gene [RGD, Feb 2006].
CIITA - Class II, Major Histocompatibility Complex, Transactivator
This gene encodes a protein with an acidic transcriptional activation domain, 4 LRRs (leucine-rich repeats) and a GTP binding domain. The protein...
| HLA-B (Major Histocompatibility Complex, Class I, B): | HLA-B Antikörper | HLA-B ELISA Kits | HLA-B Proteine |
| HLA-ABC - HLA-ABC: | HLA-ABC Antikörper | ||
| HLA-DMA - Major Histocompatibility Complex, Class II, DM alpha: | HLA-DMA Antikörper | HLA-DMA ELISA Kits | HLA-DMA Proteine |
| HLA-DMB (Major Histocompatibility Complex, Class II, DM beta): | HLA-DMB Antikörper | HLA-DMB Proteine | |
| HLA-DOB (Major Histocompatibility Complex, Class II, DO beta): | HLA-DOB Antikörper | HLA-DOB Proteine | |
| HLA-DPA1 - Major Histocompatibility Complex, Class II, DP alpha 1: | HLA-DPA1 Antikörper | HLA-DPA1 Proteine | |
| HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1): | HLA-DPB1 Antikörper | HLA-DPB1 Proteine | |
| HLA-DQA1 - Major Histocompatibility Complex, Class II, DQ alpha 1: | HLA-DQA1 Antikörper | HLA-DQA1 Proteine | |
| HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ beta 1): | HLA-DQB1 Antikörper | HLA-DQB1 ELISA Kits | HLA-DQB1 Proteine |
| HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1): | HLA-DRB1 Antikörper | HLA-DRB1 ELISA Kits | HLA-DRB1 Proteine |
| HLA-DRB3 (Major Histocompatibility Complex, Class II, DR beta 3): | HLA-DRB3 Antikörper | HLA-DRB3 Proteine | |
| HLA-DRB5 (Major Histocompatibility Complex, Class II, DR beta 5): | HLA-DRB5 Antikörper | HLA-DRB5 ELISA Kits | HLA-DRB5 Proteine |
| PTCRA (Pre T-Cell Antigen Receptor alpha): | PTCRA Antikörper | PTCRA Proteine | |
| CD74 (HLA-DR-gamma): | CD74 Antikörper | CD74 ELISA Kits | CD74 Proteine |
Stimulatory T-Cell Receptors
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4):
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond,...
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CD274 - PD-L1
Involved in the costimulatory signal essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1...
TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4):
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for...
Cytokines
IL1A (Interleukin 1 alpha):
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various...
IL1B (Interleukin 1, beta):
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a...
| IL1F6 - Interleukin 1 Family, Member 6: | IL1F6 Antikörper | IL1F6 ELISA Kits | IL1F6 Proteine |
| IL1RN (Interleukin 1 Receptor Antagonist): | IL1RN Antikörper | IL1RN ELISA Kits | IL1RN Proteine |
| IL10 - IL-10: | IL10 Antikörper | IL10 ELISA Kits | IL10 Proteine |
| IL12 (Interleukin 12): | IL12 Antikörper | IL12 ELISA Kits | IL12 Proteine |
| IL18 - IL 18: | IL18 Antikörper | IL18 ELISA Kits | IL18 Proteine |
| IL6 - Interleukin 6: | IL6 Antikörper | IL6 ELISA Kits | IL6 Proteine |
| IL6RA (Interleukin 6 Receptor, alpha): | IL6RA Antikörper | IL6RA ELISA Kits | IL6RA Proteine |
| IL6ST (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor)): | IL6ST Antikörper | IL6ST ELISA Kits | IL6ST Proteine |
| IL6R - IL-6 Receptor: | IL6R Antikörper | IL6R ELISA Kits | IL6R Proteine |
| TGFB1 (Transforming Growth Factor, beta 1): | TGFB1 Antikörper | TGFB1 ELISA Kits | TGFB1 Proteine |
| IL1R1 (Interleukin 1 Receptor, Type I): | IL1R1 Antikörper | IL1R1 ELISA Kits | IL1R1 Proteine |
