Cancer Immune Checkpoints
Inhibitory T-Cell Receptors
TIM 3 - TIM3:
LAG3 - Lymphocyte-Activation Gene 3:
VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation):
TIGIT (T Cell Immunoreceptor with Ig and ITIM Domains):
BTLA (B and T Lymphocyte Associated):
TNFRSF14 - HVEM:
KIR2DL3 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 3):
TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4):
TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14):
Major Histocompatibility Complex
HLA-A (Major Histocompatibility Complex, Class I, A):
MR1 (Major Histocompatibility Complex, Class I-Related):
CIITA - Class II, Major Histocompatibility Complex, Transactivator:
HLA-B (Major Histocompatibility Complex, Class I, B):
HLA-ABC - HLA-ABC:
HLA-DMA - Major Histocompatibility Complex, Class II, DM alpha:
HLA-DMB (Major Histocompatibility Complex, Class II, DM beta):
HLA-DOB (Major Histocompatibility Complex, Class II, DO beta):
HLA-DPA1 - Major Histocompatibility Complex, Class II, DP alpha 1:
HLA-DPB1 (Major Histocompatibility Complex, Class II, DP beta 1):
HLA-DQA1 - Major Histocompatibility Complex, Class II, DQ alpha 1:
HLA-DQB1 (Major Histocompatibility Complex, Class II, DQ beta 1):
HLA-DRB1 (Major Histocompatibility Complex, Class II, DR beta 1):
HLA-DRB3 (Major Histocompatibility Complex, Class II, DR beta 3):
HLA-DRB5 (Major Histocompatibility Complex, Class II, DR beta 5):
PTCRA (Pre T-Cell Antigen Receptor alpha):
CD74 (HLA-DR-gamma):
Stimulatory T-Cell Receptors
CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4):
CD274 - PD-L1:
TNFSF4 (Tumor Necrosis Factor (Ligand) Superfamily, Member 4):
ADORA2A - Adenosine A2a Receptor:
ACVR2B - Activin A Receptor, Type IIB:
CD226 (CD226 Molecule):
CD27 (CD27 Molecule):
CD276 (CD276 Molecule):
CD40LG - CD40 Ligand:
CD40 (CD40 Molecule, TNF Receptor Superfamily Member 5):
CD70 (CD70 Molecule):
CD80 (CD80):
ICOS (Inducible T-Cell Co-Stimulator):
PVR - Poliovirus Receptor:
PDCD1 - PD-1:
TNFSF9 (Tumor Necrosis Factor (Ligand) Superfamily, Member 9):
TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18):
TNFRSF4 - Tumor Necrosis Factor Receptor Superfamily, Member 4:
Cytokines
IL1A (Interleukin 1 alpha):
IL1B (Interleukin 1, beta):
IL1F6 - Interleukin 1 Family, Member 6:
IL1RN (Interleukin 1 Receptor Antagonist):
IL10 - IL-10:
IL12 (Interleukin 12):
IL18 - IL 18:
IL6 - Interleukin 6:
IL6RA (Interleukin 6 Receptor, alpha):
IL6ST (Interleukin 6 Signal Transducer (Gp130, Oncostatin M Receptor)):
IL6R - IL-6 Receptor:
TGFB1 (Transforming Growth Factor, beta 1):
IL1R1 (Interleukin 1 Receptor, Type I):
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