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MAP2K3 Antikörper (C-Term)
MAP2K3
Reaktivität: Human, Ratte
WB, IHC (p), ICC
Polyclonal
unconjugated
Produktdetails anti-MAP2K3 Antikörper
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Target
Alle MAP2K3 Antikörper anzeigen
MAP2K3
(Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
Bindungsspezifität
Alle Epitope für MAP2K3 Antikörper
AA 320-334, C-Term
Reaktivität
Alle Reaktivitäten für MAP2K3 Antikörper
Human, Ratte
Wirt
Bitte anfragen
Klonalität
Alle Klonalitäten für MAP2K3 Antikörper
Polyklonal
Konjugat
Alle Konjugate für MAP2K3 Antikörper
Dieser MAP2K3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für MAP2K3 Antikörper
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminal of human MAP2K3 (320-334 aa), identical to the related mouse and rat sequence.
Top Product
Discover our top product MAP2K3 Primärantikörper
Alternativen
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Anwendungsinformationen
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Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Rekonstitution
0.2ml of distilled water will yield a concentration of 500µg/ml.
Buffer
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4
Konservierungsmittel
Thimerosal (Merthiolate), Sodium azide
Lagerung
-20 °C
Referenzen für anti-MAP2K3 Antikörper (ABIN966513)
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Rampoldi, Zimbello, Bortoluzzi, Tiso, Valle, Lanfranchi, Danieli : "Chromosomal localization of four MAPK signaling cascade genes: MEK1, MEK3, MEK4 and MEKK5. " in: Cytogenetics and cell genetics , Vol. 78 , Issue 3-4 , pp. 301-3 , (1998 ) (PubMed ).
Details zu MAP2K3
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Target
MAP2K3
(Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
Andere Bezeichnung
MAP2K3 (MAP2K3 Produkte )
Synonyme
MAPKK3 antikoerper, MEK3 antikoerper, MKK3 antikoerper, PRKMK3 antikoerper, SAPKK-2 antikoerper, SAPKK2 antikoerper, AW212142 antikoerper, Prkmk3 antikoerper, mMKK3b antikoerper, Mkk3 antikoerper, mitogen-activated protein kinase kinase 3 antikoerper, mitogen activated protein kinase kinase 3 antikoerper, MAP kinase activator XMEK3 antikoerper, MAP2K3 antikoerper, Map2k3 antikoerper, map2k3 antikoerper
Hintergrund
Dual specificity mitogen-activated protein kinase kinase 3 is an enzyme that in humans is encoded by the MAP2K3 gene. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. Rampoldi et al. (1997) localized the MAP2K3 gene to 17q11.2.
Pathways
MAPK Signalweg , TLR Signalweg , Activation of Innate immune Response , Toll-Like Receptors Cascades , Autophagie , Signaling Events mediated by VEGFR1 and VEGFR2
Zuletzt angesehen
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