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BRAF Antikörper
BRAF
Reaktivität: Human
WB, ELISA, IHC
Wirt: Maus
Monoclonal
1H12F1-1H12G10-1F12F11C9
unconjugated
Produktdetails anti-BRAF Antikörper
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Target
Alle BRAF Antikörper anzeigen
BRAF
(B-Raf proto-oncogene, serine/threonine kinase (BRAF))
Reaktivität
Alle Reaktivitäten für BRAF Antikörper
Human
Wirt
Alle Wirte für BRAF Antikörper
Maus
Klonalität
Alle Klonalitäten für BRAF Antikörper
Monoklonal
Konjugat
Alle Konjugate für BRAF Antikörper
Dieser BRAF Antikörper ist unkonjugiert
Applikation
Alle Applikationen für BRAF Antikörper
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
Immunogen
BRAF antibody was raised in Mouse using a purified recombinant fragment of BRAF expressed in E. coli as the immunogen.
Klon
1H12F1-1H12G10-1F12F11C9
Isotyp
IgG1
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Discover our top product BRAF Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
Lot specific
Buffer
Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Details zu BRAF
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Target
BRAF
(B-Raf proto-oncogene, serine/threonine kinase (BRAF))
Andere Bezeichnung
BRAF (BRAF Produkte )
Synonyme
B-RAF1 antikoerper, BRAF1 antikoerper, NS7 antikoerper, RAFB1 antikoerper, C-RMIL antikoerper, RMIL antikoerper, B-Raf antikoerper, braf1 antikoerper, rafb1 antikoerper, b-raf1 antikoerper, sierrabraf antikoerper, BRAF antikoerper, 9930012E13Rik antikoerper, AA120551 antikoerper, AA387315 antikoerper, AA473386 antikoerper, B-raf antikoerper, Braf-2 antikoerper, Braf2 antikoerper, C230098H17 antikoerper, C87398 antikoerper, D6Ertd631e antikoerper, braf antikoerper, fc48g01 antikoerper, wu:fc48g01 antikoerper, B-Raf proto-oncogene, serine/threonine kinase antikoerper, B-Raf proto-oncogene, serine/threonine kinase S homeolog antikoerper, Braf transforming gene antikoerper, si:dkey-222f8.3 antikoerper, BRAF antikoerper, Braf antikoerper, braf.S antikoerper, braf antikoerper, si:dkey-222f8.3 antikoerper
Hintergrund
BRAF is one of the main effectors recruited by GTP-bound Ras to activate the MEK-MAP kinase pathway. B-Raf contains three consensus Akt phosphorylation sites. B-Raf is a key regulatory molecule of the mitogen-activated protein kinase kinase (MEK), it has a long amino-terminal region,the region is essential for homo-dimerization of B-Raf and hetero-dimerization of B-Raf and c-Raf at the plasma membrane, followed by phosphorylation of Thr118 in the amino-terminal B-Raf-specific region. Notably, in calcium ionophore-stimulated HeLa cells, B-Raf could propagate signals to MEK under the basal level of GTP-Ras. Synonyms: Monoclonal BRAF antibody, Anti-BRAF antibody, V-raf murine sarcoma viral oncogene homolog B1 antibody, BRAF1 antibody, RAFB1 antibody, B-RAF1 antibody, B RAF1 antibody.
Pathways
MAPK Signalweg , RTK Signalweg , Neurotrophin Signalübertragung , Ribonucleoprotein Complex Subunit Organization , Hepatitis C , Autophagie
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