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BRAF Produkte

(B-Raf proto-oncogene, serine/threonine kinase (BRAF))
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte BRAF Kategorien

BRAF Antikörper

High quality antibodies with extensive validation data.

BRAF ELISA Kits

Reliable ELISA kits for a wide range of species.

BRAF Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene BRAF Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Dog, Human
Applikation WB, IHC, IHC (p)
Validierungen
  • (18)
Kat. Nr. ABIN1496961
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Dog, Human, Monkey, Rat
Applikation WB, IHC, IHC (p), IF
Validierungen
  • (8)
Kat. Nr. ABIN1496954
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Monkey
Applikation WB, IHC, IHC (p), IF, FACS
Validierungen
  • (9)
Kat. Nr. ABIN1496951
Menge 100 μL
Datenblatt Datenblatt

Empfohlene BRAF ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962346
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954037
Menge 96 tests
Datenblatt Datenblatt

Empfohlene BRAF Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN2715104
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7121967
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3133547
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren BRAF Produkten

Rushton, Korb, Kummer, Reichart, Fuchs-Baumgartinger, Tichy, Nell: "Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas." in: Veterinary journal (London, England : 1997), Vol. 249, pp. 33-40, (2019) (PubMed).

Arnoux, Fina, Lambert, Balandraud, Martin, Ouafik, Kanaan, Roudier, Auger: "Newly Identified BRAF Mutation in Rheumatoid Arthritis." in: Arthritis & rheumatology (Hoboken, N.J.), Vol. 68, Issue 6, pp. 1377-83, (2016) (PubMed).

Wiggans, Reilly, Kass, Maggs: "Histologic and immunohistochemical predictors of clinical behavior for feline diffuse iris melanoma." in: Veterinary ophthalmology, Vol. 19 Suppl 1, pp. 44-55, (2016) (PubMed).

Wiersma, de Bruyn, Wei, van Ginkel, Hirashima, Niki, Nishi, Zhou, Pouwels, Samplonius, Nijman, Eggleton, Helfrich, Bremer: "The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux." in: Autophagy, Vol. 11, Issue 8, pp. 1373-88, (2015) (PubMed).

Chang, Nam, Kook, Kim, Liu, Yao, Jung, Lemos, Seo, Park, Gim, Hong, Huh, Kim, Tan, Liu, Powis, Park, Liang, Kim: "HNF4? is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer." in: Gut, (2014) (PubMed).

Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).

Khatamianfar, Valiyeva, Rennie, Lu, Yang, Bauman, Moussa, Xuan: "TRIM59, a novel multiple cancer biomarker for immunohistochemical detection of tumorigenesis." in: BMJ open, Vol. 2, Issue 5, (2012) (PubMed).

Weisbart, Chan, Heinze, Mory, Nishimura, Colburn: "BRAF drives synovial fibroblast transformation in rheumatoid arthritis." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34299-303, (2010) (PubMed).

Duan, Cobb: "Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 51, pp. 22314-9, (2010) (PubMed).

Di Nicolantonio, Martini, Molinari, Sartore-Bianchi, Arena, Saletti, De Dosso, Mazzucchelli, Frattini, Siena, Bardelli: "Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 26, Issue 35, pp. 5705-12, (2008) (PubMed).

Synonyme und alternative Namen zu BRAF

B-Raf proto-oncogene, serine/threonine kinase (BRAF), B-Raf proto-oncogene, serine/threonine kinase (Braf), B-Raf proto-oncogene, serine/threonine kinase S homeolog (braf.S), B-Raf proto-oncogene, serine/threonine kinase (braf), Braf transforming gene (Braf), si:dkey-222f8.3 (si:dkey-222f8.3), 9930012E13Rik, AA120551, AA387315, AA473386, B-Raf, B-raf, B-RAF1, b-raf1, BRAF, braf, Braf-2, BRAF1, braf1, Braf2, C-RMIL, C87398, C230098H17, D6Ertd631e, fc48g01, NS7, RAFB1, rafb1, RMIL, sierrabraf, wu:fc48g01

Bezeichner auf Proteinebene für BRAF

  • 94 kDa B-raf protein
  • B-Raf proto-oncogene serine/threonine-protein kinase (p94)
  • murine sarcoma viral (v-raf) oncogene homolog B1
  • proto-oncogene B-Raf
  • serine/threonine-protein kinase B-raf
  • v-raf murine sarcoma viral oncogene homolog B1
  • B-Raf
  • B-Raf proto-oncogene serine/threonine-protein kinase
  • proto-oncogene c-Rmil
  • rmil serine/threonine-protein kinase
  • serine/threonine kinase
  • serine/threonine-protein kinase Rmil
  • serine/threonine protein kinase BRAF
  • serine/threonine-protein kinase B-raf-like
  • B-raf protein
  • uncharacterized protein LOC561722
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