BRE Produkte
(Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
Kategorien
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as an adapter that bridges the interaction between BABAM1/NBA1 and the rest of the complex, thereby being required for the complex integrity and modulating the E3 ubiquitin ligase activity of the BRCA1-BARD1 heterodimer. Probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin (By similarity).
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Ausgewählte BRE Kategorien
BRE Antikörper
High quality antibodies with extensive validation data.
BRE Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BRE Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, ICC, IP
Validierungen
- (4)
Kat. Nr.
ABIN2856093
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7265912
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7145788
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene BRE ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6225296
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BRE Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346865
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3136588
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3090443
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BRE Produkten
: "Anti-apoptotic protein BRE/BRCC45 attenuates apoptosis through maintaining the expression of caspase inhibitor XIAP in mouse Lewis lung carcinoma D122 cells." in: Apoptosis : an international journal on programmed cell death, Vol. 19, Issue 5, pp. 829-40, (2014) (PubMed).: "BRE is an antiapoptotic protein in vivo and overexpressed in human hepatocellular carcinoma." in: Oncogene, Vol. 27, Issue 9, pp. 1208-17, (2008) (PubMed).
: "A death receptor-associated anti-apoptotic protein, BRE, inhibits mitochondrial apoptotic pathway." in: The Journal of biological chemistry, Vol. 279, Issue 50, pp. 52106-16, (2004) (PubMed).
: "Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair." in: Molecular cell, Vol. 12, Issue 5, pp. 1087-99, (2003) (PubMed).
: "Expression of human BRE in multiple isoforms." in: Biochemical and biophysical research communications, Vol. 288, Issue 3, pp. 535-45, (2001) (PubMed).
: "Identification of a brain- and reproductive-organs-specific gene responsive to DNA damage and retinoic acid." in: Biochemical and biophysical research communications, Vol. 206, Issue 2, pp. 764-74, (1995) (PubMed).
Synonyme und alternative Namen zu BRE
BRISC and BRCA1 A complex member 2 (babam2), BRISC and BRCA1 A complex member 2 (BABAM2), BRISC and BRCA1 A complex member 2 (Babam2), brain and reproductive organ-expressed (TNFRSF1A modulator) (BRE), BRISC and BRCA1 A complex member 2 L homeolog (babam2.L), 6030405P19Rik, AI429776, B830038C02Rik, brcc4, BRCC4, brcc45, BRCC45, BRE, im:7141046, LOC100231620, zgc:110368Bezeichner auf Proteinebene für BRE
- BRCA1-A complex subunit BRE
- BRCA1/BRCA2-containing complex subunit 45
- Brain and reproductive organ-expressed protein
- brain and reproductive organ-expressed (TNFRSF1A modulator)
- BRCA1-A complex subunit BRE-like
- BRCA1/BRCA2-containing complex, subunit 4
- brain and reproductive organ-expressed protein
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