BRD2 Produkte
(Bromodomain Containing 2 (BRD2))
Kategorien
This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010].
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Ausgewählte BRD2 Kategorien
BRD2 Antikörper
High quality antibodies with extensive validation data.
BRD2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BRD2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, IHC, ICC, FACS
Validierungen
- (5)
Kat. Nr.
ABIN5542291
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN562664
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (4)
Kat. Nr.
ABIN7265939
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene BRD2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN428131
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BRD2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122047
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346854
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122048
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BRD2 Produkten
: "miR-126-5p promotes retinal endothelial cell survival through SetD5 regulation in neurons." in: Development (Cambridge, England), Vol. 145, Issue 1, (2018) (PubMed).: "H2A.Z.1 Monoubiquitylation Antagonizes BRD2 to Maintain Poised Chromatin in ESCs." in: Cell reports, Vol. 14, Issue 5, pp. 1142-55, (2016) (PubMed).
: "Therapeutic targeting of BET bromodomain proteins in castration-resistant prostate cancer." in: Nature, Vol. 510, Issue 7504, pp. 278-82, (2014) (PubMed).
: "Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma." in: Cancer cell, Vol. 24, Issue 5, pp. 603-16, (2013) (PubMed).
: "BRD2 (RING3) is a probable major susceptibility gene for common juvenile myoclonic epilepsy." in: American journal of human genetics, Vol. 73, Issue 2, pp. 261-70, (2003) (PubMed).
: "Reproductive cycle regulation of nuclear import, euchromatic localization, and association with components of Pol II mediator of a mammalian double-bromodomain protein." in: Molecular endocrinology (Baltimore, Md.), Vol. 16, Issue 8, pp. 1727-37, (2002) (PubMed).
: "RING3 kinase transactivates promoters of cell cycle regulatory genes through E2F." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 11, Issue 8, pp. 417-24, (2000) (PubMed).
Synonyme und alternative Namen zu BRD2
Ring3 protein (CHLREDRAFT_190116), Ring3 protein (CHLREDRAFT_150233), Ring3 protein (CHLREDRAFT_182576), Ring3 protein (CHLREDRAFT_188250), bromodomain containing 2 (BRD2), bromodomain containing 2 (Brd2), bromodomain containing 2 S homeolog (brd2.S), bromodomain containing 2a (brd2a), AW228947, brd2, brd2-a, D6S113E, D17H6S113E, fe47f02, fi85h05, Frg-1, FSH, fsh, Fsrg-1, FSRG1, Fsrg1, fsrg1, mKIAA4005, NAT, Nat, nat, RING3, Ring3, ring3, RNF3, Rnf3, rnf3, wu:fe47f02, wu:fi85h05Bezeichner auf Proteinebene für BRD2
- Ring3 protein
- O27.1.1
- bromodomain-containing 2
- bromodomain-containing protein 2
- female sterile homeotic-related gene 1
- really interesting new gene 3 protein
- collagen type XI alpha 2
- glutamate-cysteine ligase catalytic subunit
- ring finger protein 3
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