PDK2 Antikörper (AA 315-407) (Alexa Fluor 555)

Produktnummer ABIN910590

Produktdetails anti-PDK2 Antikörper (Alexa Fluor 555)

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Bindungsspezifität: AA 315-407

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDK2 Antikörper ist konjugiert mit Alexa Fluor 555

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDK2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PDK2

Target: PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))

Andere Bezeichnung: PDK2 (PDK2 Produkte)

Synonyme: PDHK2 antikoerper, PDKII antikoerper, Pdk antikoerper, zgc:56209 antikoerper, PDK2 antikoerper, pyruvate dehydrogenase kinase 2 antikoerper, pyruvate dehydrogenase kinase, isoenzyme 2 antikoerper, pyruvate dehydrogenase kinase, isozyme 2b antikoerper, PDK2 antikoerper, Pdk2 antikoerper, pdk2b antikoerper

Hintergrund:

Synonyms: PDHK2, Pyruvate dehydrogenase kinase isoform 2, pyruvate dehydrogenase kinase, isozyme 2, Pyruvate dehydrogenase lipoamide kinase isozyme 2, mitochondrial, PDK2_HUMAN.

Background: This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].

Gen-ID: 5164

Pathways: PI3K-Akt Signalweg, RTK Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt