PDK2 Antikörper (AA 128-407)
Kurzübersicht für PDK2 Antikörper (AA 128-407) (ABIN1681304)
Target
Alle PDK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 128-407
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Sequenz
- PTMAQGVLEY KDTYGDDPVS NQNIQYFLDR FYLSRISIRM LINQHTLIFD GSTNPAHPKH IGSIDPNCNV SEVVKDAYDM AKLLCDKYYM ASPDLEIQEI NAANSKQPIH MVYVPSHLYH MLFELFKNAM RATVESHESS LILPPIKVMV ALGEEDLSIK MSDRGGGVPL RKIERLFSYM YSTAPTPQPG TGGTPLAGFG YGLPISRLYA KYFQGDLQLF SMEGFGTDAV IYLKALSTDS VERLPVYNKS AWRHYQTIQE AGDWCVPSTE PKNTSTYRVS
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Kreuzreaktivität
- Human
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 128-407 of human PDK2 (NP_002602.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- PDK2 (Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
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Andere Bezeichnung
- PDK2
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Hintergrund
- This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,PDK2,PDHK2,PDKII,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Warburg Effect,PDK2
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Molekulargewicht
- 38 kDa/46 kDa
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Gen-ID
- 5164
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UniProt
- Q15119
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Pathways
- PI3K-Akt Signalweg, RTK Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
Target
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