PDK2 Produkte
(Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
Kategorien
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
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Ausgewählte PDK2 Kategorien
PDK2 Antikörper
High quality antibodies with extensive validation data.
PDK2 ELISA Kits
Reliable ELISA kits for a wide range of species.
PDK2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PDK2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), RNAi
Validierungen
- (4)
- (6)
Kat. Nr.
ABIN562160
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7439423
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS
Validierungen
- (5)
Kat. Nr.
ABIN5542665
Menge
0.1 mg
Datenblatt
Datenblatt
Empfohlene PDK2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6959010
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5658317
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6231784
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PDK2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5570520
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314549
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314551
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PDK2 Produkten
: "PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3." in: Journal of drug targeting, Vol. 27, Issue 4, pp. 460-465, (2019) (PubMed).: "Selective Phosphorylation Inhibitor of Delta Protein Kinase C-Pyruvate Dehydrogenase Kinase Protein-Protein Interactions: Application for Myocardial Injury in Vivo." in: Journal of the American Chemical Society, Vol. 138, Issue 24, pp. 7626-35, (2018) (PubMed).
: "Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death." in: The Journal of biological chemistry, Vol. 291, Issue 26, pp. 13608-21, (2016) (PubMed).
: "Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study." in: Diabetes, Vol. 64, Issue 8, pp. 2735-43, (2015) (PubMed).
: "Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation." in: Journal of cell science, Vol. 128, Issue 13, pp. 2319-29, (2015) (PubMed).
: "Retinoic acid-related orphan receptor alpha reprograms glucose metabolism in glutamine-deficient hepatoma cells." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 3, pp. 953-64, (2015) (PubMed).
: "Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species." in: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 35153-60, (2012) (PubMed).
: "p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2." in: Cancer research, Vol. 72, Issue 2, pp. 560-7, (2012) (PubMed).
: "Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPAR?-independent mechanisms." in: European journal of cell biology, Vol. 90, Issue 8, pp. 657-64, (2011) (PubMed).
: "The relationship between human skeletal muscle pyruvate dehydrogenase phosphatase activity and muscle aerobic capacity." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 111, Issue 2, pp. 427-34, (2011) (PubMed).
Synonyme und alternative Namen zu PDK2
pyruvate dehydrogenase kinase 2 (PDK2), pyruvate dehydrogenase kinase, isoenzyme 2 (Pdk2), pyruvate dehydrogenase kinase 2 (Pdk2), pyruvate dehydrogenase kinase, isozyme 2b (pdk2b), PDHK2, Pdk, PDK2, PDKII, zgc:56209Bezeichner auf Proteinebene für PDK2
- PDH kinase 2
- pyruvate dehydrogenase kinase, isoenzyme 2
- pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial
- [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial
- pyruvate dehydrogenase 2
- pyruvate dehydrogenase kinase, isozyme 2
- PDK P45
- pyruvate dehydrogenase kinase 2 subunit p45 (PDK2)
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