PDK4 Produkte
(Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
Kategorien
This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq, Jul 2008].
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Ausgewählte PDK4 Kategorien
PDK4 Antikörper
High quality antibodies with extensive validation data.
PDK4 ELISA Kits
Reliable ELISA kits for a wide range of species.
PDK4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PDK4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, IHC (p)
Validierungen
- (24)
- (6)
Kat. Nr.
ABIN391039
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7439630
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, IF, mIHC
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN3028963
Menge
0.2 mL
Datenblatt
Datenblatt
Empfohlene PDK4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969802
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953337
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
Kat. Nr.
ABIN1116875
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PDK4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (2)
Kat. Nr.
ABIN5570522
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7124722
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314556
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PDK4 Produkten
: "Immune Checkpoint Blockade Improves Chemotherapy in the PyMT Mammary Carcinoma Mouse Model." in: Frontiers in oncology, Vol. 10, pp. 1771, (2020) (PubMed).: "High hepatic expression of PDK4 improves survival upon multimodal treatment of colorectal liver metastases." in: British journal of cancer, Vol. 120, Issue 7, pp. 675-688, (2019) (PubMed).
: "Overexpression of lncRNA EPB41L4A-AS1 Induces Metabolic Reprogramming in Trophoblast Cells and Placenta Tissue of Miscarriage." in: Molecular therapy. Nucleic acids, Vol. 18, pp. 518-532, (2019) (PubMed).
: "Defining the contribution of skeletal muscle pyruvate dehydrogenase alpha 1 (Pdha1) to exercise performance and insulin action." in: American journal of physiology. Endocrinology and metabolism, (2018) (PubMed).
: "The antineoplastic drug, trastuzumab, dysregulates metabolism in iPSC-derived cardiomyocytes." in: Clinical and translational medicine, Vol. 6, Issue 1, pp. 5, (2017) (PubMed).
: "On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 30, Issue 8, pp. 2684-97, (2017) (PubMed).
: "Arsenic silences hepatic PDK4 expression through activation of histone H3K9 methylatransferase G9a." in: Toxicology and applied pharmacology, Vol. 304, pp. 42-7, (2017) (PubMed).
: "Transforming Growth Factor β Mediates Drug Resistance by Regulating the Expression of Pyruvate Dehydrogenase Kinase 4 in Colorectal Cancer." in: The Journal of biological chemistry, Vol. 291, Issue 33, pp. 17405-16, (2017) (PubMed).
: "The microRNA-182-PDK4 axis regulates lung tumorigenesis by modulating pyruvate dehydrogenase and lipogenesis." in: Oncogene, Vol. 36, Issue 7, pp. 989-998, (2017) (PubMed).
: "Pyruvate dehydrogenase kinase 4 exhibits a novel role in the activation of mutant KRAS, regulating cell growth in lung and colorectal tumour cells." in: Oncogene, Vol. 36, Issue 44, pp. 6164-6176, (2017) (PubMed).
Synonyme und alternative Namen zu PDK4
pyruvate dehydrogenase kinase 4 (pdk4), pyruvate dehydrogenase kinase 4 (PDK4), pyruvate dehydrogenase kinase, isoenzyme 4 (Pdk4), pyruvate dehydrogenase kinase 4 (Pdk4), AV005916Bezeichner auf Proteinebene für PDK4
- pyruvate dehydrogenase kinase 4
- pyruvate dehydrogenase kinase, isoenzyme 4
- pyruvate dehydrogenase kinase, isozyme 4
- [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 4, mitochondrial
- pyruvate dehydrogenase, lipoamide, kinase isozyme 4, mitochondrial
- pyruvate dehydrogenase kinase isozyme 4
- pyruvate dehydrogenate kinase 4
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