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PDGFB Produkte

(Platelet Derived Growth Factor Subunit B (PDGFB))

Kategorien

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2013].

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Ausgewählte PDGFB Kategorien

PDGFB Antikörper

High quality antibodies with extensive validation data.

PDGFB ELISA Kits

Reliable ELISA kits for a wide range of species.

PDGFB Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PDGFB Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IF, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN7223038
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (5)
Kat. Nr. ABIN3021689
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (4)
  • (3)
Kat. Nr. ABIN725990
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PDGFB ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958642
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6958644
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6969404
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PDGFB Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (2)
Kat. Nr. ABIN5509325
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314500
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7124479
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PDGFB Produkten

Zhu, Ma, Dong, Shang, Gu, Zi: "Melatonin promotes osteoblastic differentiation and regulates PDGF/AKT signaling pathway." in: Cell biology international, Vol. 44, Issue 2, pp. 402-411, (2020) (PubMed).

Kurys-Denis, Prystupa, Luchowska-Kocot, Krupski, Bis-Wencel, Panasiuk: "PDGF-BB homodimer serum level - a good indicator of the severity of alcoholic liver cirrhosis." in: Annals of agricultural and environmental medicine : AAEM, Vol. 27, Issue 1, pp. 80-85, (2020) (PubMed).

Zhang, Deng, Zhang, Liu, Zhang, Zhu, Tang, Deng: "The Design, Characterizations, and Tumor Angiogenesis Inhibition of a Multi-Epitope Peptibody With bFGF/VEGFA." in: Frontiers in oncology, Vol. 10, pp. 1190, (2020) (PubMed).

Xu, Tian, Cheng, Liang, Li, Liu: "Immunohistochemical biomarkers and distribution of telocytes in ApoE-/- mice." in: Cell biology international, Vol. 43, Issue 11, pp. 1286-1295, (2020) (PubMed).

Giusti, Di Francesco, DAscenzo, Palumbo, Rughetti, DellOrso, Varasano, Pressanti, Dolo: "Leukocyte depletion does not affect the in vitro healing ability of platelet rich plasma." in: Experimental and therapeutic medicine, Vol. 15, Issue 4, pp. 4029-4038, (2018) (PubMed).

Ulvé, Rault, Bahin, Lagoutte, Abadie, De Brito, Coindre, Botherel, Rousseau, Wucher, Cadieu, Thieblemont, Hitte, Cornevin, Cabillic, Bachelot, Gilot, Hennuy, Guillaudeux, Le Goff, Derrien, Hédan et al.: "Discovery of Human-Similar Gene Fusions in Canine Cancers. ..." in: Cancer research, Vol. 77, Issue 21, pp. 5721-5727, (2017) (PubMed).

Shang, Zhao, Wang, Wang, Sui, Mi: "Expression and purification of functional PDGF receptor beta." in: Biochemical and biophysical research communications, Vol. 489, Issue 3, pp. 353-359, (2017) (PubMed).

Salva, Turan, Akbuğa: "Inhibition of Glomerular Mesangial Cell Proliferation by siPDGF-B- and siPDGFR-β-Containing Chitosan Nanoplexes." in: AAPS PharmSciTech, Vol. 18, Issue 4, pp. 1031-1042, (2016) (PubMed).

Morita, Furube, Mannari, Okuda, Tatsumi, Wanaka, Miyata: "Vascular endothelial growth factor-dependent angiogenesis and dynamic vascular plasticity in the sensory circumventricular organs of adult mouse brain." in: Cell and tissue research, (2015) (PubMed).

Lee, Zheng, Kang, Kim, Oh, Cho: "Therapeutic efficacy of autologous platelet-rich plasma and polydeoxyribonucleotide on female pattern hair loss." in: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, (2015) (PubMed).

Synonyme und alternative Namen zu PDGFB

platelet derived growth factor subunit B (PDGFB), platelet-derived growth factor beta polypeptide (PDGFB), platelet derived growth factor subunit B S homeolog (pdgfb.S), platelet-derived growth factor beta polypeptide a (pdgfba), platelet derived growth factor, B polypeptide (Pdgfb), platelet derived growth factor subunit B (Pdgfb), c-sis, PDGF-2, PDGF-B, PDGF2, pdgf2, si:ch211-79m20.1, si:dkey-261d11.1, SIS, sis, Sis, SSV

Bezeichner auf Proteinebene für PDGFB

  • PDGF subunit B
  • PDGF, B chain
  • becaplermin
  • platelet-derived growth factor 2
  • platelet-derived growth factor B chain
  • platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
  • platelet-derived growth factor subunit B
  • platelet-derived growth factor, beta polypeptide (oncogene SIS)
  • proto-oncogene c-Sis
  • platelet-derived growth factor B
  • v-sis platelet-derived growth factor beta polypeptide (simian sarcoma viral oncogene homolog)
  • PDGF-2
  • c-sis
  • platelet-derived growth factor beta polypeptide
  • Platelet-derived growth factor, same as Sis (Simian sarcoma viral oncogene homologue, c-sis)
  • pdgf protein
  • platelet derived growth factor, B polypeptide
  • platelet-derived growth factor B subunit
  • Platelet-derived growth factor B chain
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