PDE8A Produkte
(phosphodiesterase 8A (PDE8A))
Kategorien
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011].
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Ausgewählte PDE8A Kategorien
PDE8A Antikörper
High quality antibodies with extensive validation data.
PDE8A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PDE8A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN518727
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
- (2)
Kat. Nr.
ABIN542843
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7155164
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PDE8A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6232261
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PDE8A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314488
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314490
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3094410
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PDE8A Produkten
: "Cyclic nucleotide phosphodiesterases in human spermatozoa and seminal fluid: Presence of an active PDE10A in human spermatozoa." in: Biochimica et biophysica acta, Vol. 1861, Issue 2, pp. 147-156, (2017) (PubMed).: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).
: "Select 3',5'-cyclic nucleotide phosphodiesterases exhibit altered expression in the aged rodent brain." in: Cellular signalling, Vol. 26, Issue 2, pp. 383-97, (2014) (PubMed).
: "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." in: The Biochemical journal, Vol. 456, Issue 3, pp. 463-73, (2013) (PubMed).
: "Distribution of PDE8A in the nervous system of the Sprague-Dawley rat." in: Journal of chemical neuroanatomy, Vol. 42, Issue 3, pp. 184-91, (2012) (PubMed).
: "Polymorphism in HIV-1 dependency factor PDE8A affects mRNA level and HIV-1 replication in primary macrophages." in: Virology, Vol. 420, Issue 1, pp. 32-42, (2011) (PubMed).
: "Per-Arnt-Sim domain-dependent association of cAMP-phosphodiesterase 8A1 with IkappaB proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 51, pp. 17634-9, (2004) (PubMed).
: "Comparison of enzymatic characterization and gene organization of cyclic nucleotide phosphodiesterase 8 family in humans." in: Cellular signalling, Vol. 15, Issue 6, pp. 565-74, (2003) (PubMed).
: "Tyrosine kinase activation in response to fungal spores is primarily dependent on endogenous reactive oxygen production in macrophages." in: The Journal of biological chemistry, Vol. 275, Issue 14, pp. 10175-81, (2000) (PubMed).
: "An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo." in: The Journal of biological chemistry, Vol. 270, Issue 35, pp. 20832-40, (1995) (PubMed).
Synonyme und alternative Namen zu PDE8A
phosphodiesterase 8A (PDE8A), phosphodiesterase 8A (Pde8a), phosphodiesterase 8A (pde8a), AI551852, HsT19550, Pde8, PDE8A, Pde8a, RNPDE8ABezeichner auf Proteinebene für PDE8A
- phosphodiesterase 8A
- high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
- phosphodiesterase 8a
- high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A-like
- cAMP-specific cyclic nucleotide phosphodiesterase 8A
- mmPDE8
- cAMP-specific cyclic nucleotide phosphodiesterase PDE8
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