PDE4A Produkte
(phosphodiesterase 4A, CAMP-Specific (PDE4A))
Kategorien
The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].
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Ausgewählte PDE4A Kategorien
PDE4A Antikörper
High quality antibodies with extensive validation data.
PDE4A Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene PDE4A Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, FACS, IHC (p)
Validierungen
- (7)
Kat. Nr.
ABIN1500089
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7243706
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7269302
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene PDE4A ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6231741
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene PDE4A Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1314462
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2728507
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3094538
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren PDE4A Produkten
: "CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system-New mode of action for caffeine. ..." in: PLoS biology, Vol. 16, Issue 6, pp. e2004408, (2018) (PubMed).: "The Regulatory Role of Rolipram on Inflammatory Mediators and Cholinergic/Adrenergic Stimulation-Induced Signals in Isolated Primary Mouse Submandibular Gland Cells." in: Mediators of inflammation, Vol. 2016, pp. 3745961, (2017) (PubMed).
: "Dysregulation of hepatic cAMP levels via altered Pde4b expression plays a critical role in alcohol-induced steatosis." in: The Journal of pathology, Vol. 240, Issue 1, pp. 96-107, (2017) (PubMed).
: "Resveratrol directly targets DDX5 resulting in suppression of the mTORC1 pathway in prostate cancer." in: Cell death & disease, Vol. 7, pp. e2211, (2016) (PubMed).
: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).
: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).
: "Expression and distribution of phosphodiesterase isoenzymes in the human male urethra." in: Urology, Vol. 85, Issue 4, pp. 964.e1-6, (2015) (PubMed).
: "NCS 613 exhibits anti-inflammatory effects on PBMCs from lupus patients by inhibiting p38 MAPK and NF-κB signalling pathways while reducing proinflammatory cytokine production." in: Canadian journal of physiology and pharmacology, Vol. 91, Issue 5, pp. 353-61, (2014) (PubMed).
: "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." in: Neuroscience, Vol. 263, pp. 1-14, (2014) (PubMed).
: "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." in: Cellular signalling, Vol. 26, Issue 5, pp. 1001-10, (2014) (PubMed).
Synonyme und alternative Namen zu PDE4A
phosphodiesterase 4A S homeolog (pde4a.S), phosphodiesterase 4A, cAMP-specific (pde4a), phosphodiesterase 4A (PDE4A), phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila) (PDE4A), cAMP-specific 3',5'-cyclic phosphodiesterase 4A (LOC100009247), phosphodiesterase 4A (Pde4a), phosphodiesterase 4A (pde4a), phosphodiesterase 4A, cAMP specific (Pde4a), phosphodiesterase 4C (PDE4C), phosphodiesterase 4A, cAMP-specific (PDE4A), D9Ertd60e, dpde2, Dpde2, DPDE2, pde4, PDE4, PDE4A, Pde4a, pde46, PDE46, PHOSABezeichner auf Proteinebene für PDE4A
- phosphodiesterase 4A, cAMP-specific
- phosphodiesterase 4A-like
- phosphodiesterase 4A, cAMP-specific (phosphodiesterase E2 dunce homolog, Drosophila)
- cyclic AMP-specific phosphodiesterase FCPDE4A1A
- cyclic AMP-specific phosphodiesterase OCPDE4A1A
- phosphodiesterase 4A, cAMP specific
- cyclic AMP-specific phosphodiesterase CPPDE4A1A
- cAMP-specific 3',5'-cyclic phosphodiesterase 4A
- cAMP-specific phosphodiesterase PDE4A
- cyclic AMP specific phosphodiesterase PDE4A5A
- dunce
- phosphodiesterase 4A, cAMP-specific (dunce
- phosphodiesterase E2 dunce homolog, Drosophila
- phosphodiesterase isozyme 4
- DPDE2
- cyclic AMP-specific phosphodiesterase SSPDE4A1A
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