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PDE1A Produkte

(Phosphodiesterase 1A (PDE1A))

Kategorien

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1\; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]\; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009].

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Ausgewählte PDE1A Kategorien

PDE1A Antikörper

High quality antibodies with extensive validation data.

PDE1A ELISA Kits

Reliable ELISA kits for a wide range of species.

PDE1A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene PDE1A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (3)
Kat. Nr. ABIN7441283
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Dog, Human, Mouse, Rat
Applikation WB
Validierungen
  • (4)
Kat. Nr. ABIN2785487
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN6264086
Menge 100 μL
Datenblatt Datenblatt

Empfohlene PDE1A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6958529
Menge 96 tests
Datenblatt Datenblatt

Empfohlene PDE1A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314449
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1314451
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3085619
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren PDE1A Produkten

Rajagopal, Nalli, Kumar, Bhattacharya, Hu, Mahavadi, Grider, Murthy: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." in: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).

Kedia, Ückert, Oelke, Sonnenberg, Sohn, Kuczyk, Hedlund: "Expression and distribution of phosphodiesterase isoenzymes in the human male urethra." in: Urology, Vol. 85, Issue 4, pp. 964.e1-6, (2015) (PubMed).

Uckert, Albrecht, Kuczyk, Hedlund, Oelke: "Phosphodiesterase type 1, calcitonin gene-related peptide and vasoactive intestinal polypeptide are involved in the control of human vaginal arterial vessels." in: European journal of obstetrics, gynecology, and reproductive biology, Vol. 169, Issue 2, pp. 283-6, (2014) (PubMed).

Yougbaré, Keravis, Abusnina, Decossas, Schall, Muller, Lugnier: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." in: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).

Abusnina, Keravis, Yougbaré, Bronner, Lugnier: "Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1." in: Molecular nutrition & food research, Vol. 55, Issue 11, pp. 1677-89, (2012) (PubMed).

Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." in: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

Genders, Bradley, Rattigan, Richards: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." in: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).

Cabanero, Laje, Detera-Wadleigh, McMahon: "Association study of phosphodiesterase genes in the Sequenced Treatment Alternatives to Relieve Depression sample." in: Pharmacogenetics and genomics, Vol. 19, Issue 3, pp. 235-8, (2009) (PubMed).

Ortiz-Capisano, Liao, Ortiz, Beierwaltes: "Calcium-dependent phosphodiesterase 1C inhibits renin release from isolated juxtaglomerular cells." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 297, Issue 5, pp. R1469-76, (2009) (PubMed).

Deplano, Giorgi, Maccarone, Santone, Nuccetelli, Basso, Bisti: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase during ontogenesis of chick retina." in: Journal of neuroscience research, Vol. 86, Issue 5, pp. 1017-23, (2008) (PubMed).

Synonyme und alternative Namen zu PDE1A

phosphodiesterase 1A (PDE1A), phosphodiesterase 1A, calmodulin-dependent (pde1a), phosphodiesterase 1A (pde1a), phosphodiesterase 1A, calmodulin-dependent (PDE1A), phosphodiesterase 1A (Pde1a), phosphodiesterase 1A, calmodulin-dependent (Pde1a), 3'-RACEclone8phosphodiesterase1A, 3-RACEclone8phosphodiesterase1A, AI987702, AW125737, CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A, PDE1, PDE1A

Bezeichner auf Proteinebene für PDE1A

  • calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
  • calmodulin-activated cyclic nucleotide phosphodiesterase
  • phosphodiesterase 1A, calmodulin-dependent
  • calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like
  • cyclic nucleotide phosphodiesterase 1a
  • 61 kDa Cam-PDE
  • calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase
  • cam-PDE 1A
  • 3'-RACE clone 8 phosphodiesterase 1A
  • 3-RACE clone 8 phosphodiesterase 1A
  • calmodulin-dependent phosphodiesterase type 1
  • nucleotide phosphodiesterase, 3'-5'-cyclic
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