PSMD14 Antikörper (AA 101-200) (Alexa Fluor 488)
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- Target Alle PSMD14 Antikörper anzeigen
- PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))
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Bindungsspezifität
- AA 101-200
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PSMD14 Antikörper ist konjugiert mit Alexa Fluor 488
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse,Rat,Cow,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MAD1
- Isotyp
- IgG
- Top Product
- Discover our top product PSMD14 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))
- Andere Bezeichnung
- Mad1 (PSMD14 Produkte)
- Synonyme
- PAD1 antikoerper, POH1 antikoerper, RPN11 antikoerper, 2610312C03Rik antikoerper, 3200001M20Rik antikoerper, AA986732 antikoerper, Pad1 antikoerper, Poh1 antikoerper, rpm11 antikoerper, zgc:162272 antikoerper, proteasome 26S subunit, non-ATPase 14 antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 antikoerper, 26S proteasome non-ATPase regulatory subunit 14 antikoerper, proteasome 26S subunit, non-ATPase 14 L homeolog antikoerper, 26S proteasome-associated pad1 homolog antikoerper, PSMD14 antikoerper, Psmd14 antikoerper, rpn-11 antikoerper, psmd14 antikoerper, psmd14.L antikoerper
- Hintergrund
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Synonyms: mitosis arrest deficiency 1, hMAD1, HsMAD1, MAD1L1, Mitotic arrest deficient 1, Mitotic checkpoint MAD1 protein homolog, Mitotic spindle assembly checkpoint protein MAD1, PIG9, Tax binding protein 181, TP53I9 , Tumor protein p53 inducible protein 9, TXBP181, MD1L1_HUMAN.
Background: spindle microtubules. The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators. Like other spindle checkpoint mutants, MAD1 loss-of-function mutants are sensitive to benomyl and cannot delay cell division in response to spindle depolymerization. Mad1p becomes hyperphosphorylated upon spindle depolymerization.
- Gen-ID
- 8379
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway
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