PSMD14 Antikörper (AA 362-632)

Produktnummer ABIN3032352

Produktdetails anti-PSMD14 Antikörper

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Bindungsspezifität: AA 362-632

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMD14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 362-632) was used as the immunogen for this MAD1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the MAD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the MAD1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu PSMD14

Target: PSMD14 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 14 (PSMD14))

Andere Bezeichnung: MAD1 (PSMD14 Produkte)

Synonyme: PAD1 antikoerper, POH1 antikoerper, RPN11 antikoerper, 2610312C03Rik antikoerper, 3200001M20Rik antikoerper, AA986732 antikoerper, Pad1 antikoerper, Poh1 antikoerper, rpm11 antikoerper, zgc:162272 antikoerper, proteasome 26S subunit, non-ATPase 14 antikoerper, proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 antikoerper, 26S proteasome non-ATPase regulatory subunit 14 antikoerper, proteasome 26S subunit, non-ATPase 14 L homeolog antikoerper, 26S proteasome-associated pad1 homolog antikoerper, PSMD14 antikoerper, Psmd14 antikoerper, rpn-11 antikoerper, psmd14 antikoerper, psmd14.L antikoerper

Hintergrund: Mitotic spindle assembly checkpoint protein MAD1 is a protein that in humans is encoded by the MAD1L1 gene. It is mapped to 7p22.3. MAD1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. It can function as a homodimer. It localizes to the centrosome during metaphase and to the spindle midzone and the midbody during anaphase and telophase. MAD1 may also play a role in cell cycle control and tumor suppression.

Gen-ID: 8379

UniProt: Q9Y6D9

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Ubiquitin Proteasome Pathway