NLRP1 Antikörper (AA 301-400) (Alexa Fluor 350)

Produktnummer ABIN886487

Produktdetails anti-NLRP1 Antikörper (Alexa Fluor 350)

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Bindungsspezifität: AA 301-400

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP1 Antikörper ist konjugiert mit Alexa Fluor 350

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CARD7/NALP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NLRP1

Target: NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

Andere Bezeichnung: CARD7 (NLRP1 Produkte)

Synonyme: CARD7 antikoerper, CIDED antikoerper, CLR17.1 antikoerper, DEFCAP antikoerper, DEFCAP-L/S antikoerper, NAC antikoerper, NALP1 antikoerper, PP1044 antikoerper, SLEV1 antikoerper, VAMAS1 antikoerper, NLR family pyrin domain containing 1 antikoerper, NLRP1 antikoerper, Nlrp1 antikoerper

Hintergrund:

Synonyms: LRR and PYD domains-containing protein 1, CARD 7, CARD7, Caspase recruitment domain protein 7, Caspase recruitment domain-containing protein 7, CLR17.1, Death effector filament forming Ced 4 like apoptosis protein, Death effector filament-forming ced-4-like apoptosis protein, DEFCAP, DEFCAP L/S, NAC alpha/beta/gamma/delta, NAC, NACHT, NACHT leucine rich repeat and PYD containing 1, NACHT leucine rich repeat and PYD pyrin domain containing 1, NACHT leucine rich repeat and pyrin domain containing 1, NACHT LRR and PYD containing protein 1, NALP 1, NALP1, NALP1_HUMAN, NLR family pyrin domain containing 1, NLRP 1, NLRP1, NLRP1 protein, Nucleotide binding domain and caspase recruitment domain, Nucleotide binding oligomerization domain leucine rich repeat and pyrin domain containing 1, Nucleotide-binding domain and caspase recruitment domain, PP 1044, PP1044.

Background: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].

Gen-ID: 22861

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome