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NLRP1 Antikörper

NLRP1 Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7074850
  • Target Alle NLRP1 Antikörper anzeigen
    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
    Reaktivität
    • 38
    • 17
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 35
    • 2
    • 1
    Kaninchen
    Klonalität
    • 38
    Polyklonal
    Konjugat
    • 17
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NLRP1 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 13
    • 13
    • 11
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein corresponding to Mouse NLRP1
    Top Product
    Discover our top product NLRP1 Primärantikörper
  • Applikationshinweise
    IHC/IF (M,R) 1:500-1:2000/1:250-1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
    Andere Bezeichnung
    NLRP1 (NLRP1 Produkte)
    Synonyme
    CARD7 antikoerper, CIDED antikoerper, CLR17.1 antikoerper, DEFCAP antikoerper, DEFCAP-L/S antikoerper, NAC antikoerper, NALP1 antikoerper, PP1044 antikoerper, SLEV1 antikoerper, VAMAS1 antikoerper, NLR family pyrin domain containing 1 antikoerper, NLRP1 antikoerper, Nlrp1 antikoerper
    Hintergrund
    NACHT, LRR and PYD domains-containing protein 1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. The NLRP1 protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
    Gen-ID
    195046
    NCBI Accession
    NP_001004142
    UniProt
    Q2LKU9
    Pathways
    Positive Regulation of Endopeptidase Activity, Inflammasome
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