NLRP1 Produkte
(NLR Family, Pyrin Domain Containing 1 (NLRP1))
Kategorien
This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].
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Ausgewählte NLRP1 Kategorien
NLRP1 Antikörper
High quality antibodies with extensive validation data.
NLRP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Empfohlene NLRP1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (7)
Kat. Nr.
ABIN7268935
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7160821
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Horse, Human, Monkey, Mouse
Applikation
WB, IHC, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN768983
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene NLRP1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6968954
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6974912
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene NLRP1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
- (1)
Kat. Nr.
ABIN3094175
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2713167
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren NLRP1 Produkten
: "Reduction of SIRT1 epigenetically upregulates NALP1 expression and contributes to neuropathic pain induced by chemotherapeutic drug bortezomib." in: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 292, (2019) (PubMed).: "Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury." in: Frontiers in molecular neuroscience, Vol. 12, pp. 36, (2019) (PubMed).
: "Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination." in: Metabolic brain disease, (2019) (PubMed).
: "Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke." in: Journal of biophotonics, (2017) (PubMed).
: "NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model." in: Journal of neuroinflammation, Vol. 12, pp. 18, (2015) (PubMed).
: "Intermittent fasting attenuates inflammasome activity in ischemic stroke." in: Experimental neurology, Vol. 257, pp. 114-9, (2014) (PubMed).
: "Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke." in: Cell death & disease, Vol. 4, pp. e790, (2013) (PubMed).
: "NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1? processing via the NLRP1 inflammasome." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 8, pp. 2952-6, (2013) (PubMed).
: "Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes." in: The Journal of allergy and clinical immunology, Vol. 127, Issue 3, pp. 806-14.e1-4, (2011) (PubMed).
: "Inflammasome mRNA expression in human monocytes during early septic shock." in: American journal of respiratory and critical care medicine, Vol. 177, Issue 9, pp. 983-8, (2008) (PubMed).
Synonyme und alternative Namen zu NLRP1
NLR family pyrin domain containing 1 (NLRP1), NLR family pyrin domain containing 1 (Nlrp1), CARD7, CIDED, CLR17.1, DEFCAP, DEFCAP-L/S, NAC, NALP1, PP1044, SLEV1, VAMAS1Bezeichner auf Proteinebene für NLRP1
- NACHT, LRR and PYD containing protein 1
- NACHT, LRR and PYD domains-containing protein 1
- NACHT, leucine rich repeat and PYD (pyrin domain) containing 1
- NACHT, leucine rich repeat and PYD containing 1
- caspase recruitment domain protein 7
- caspase recruitment domain-containing protein 7
- death effector filament-forming Ced-4-like apoptosis protein
- nucleotide-binding domain and caspase recruitment domain
- nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1
- NLR family, pyrin domain containing 1
- NLR family pyrin domain containing 1
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