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FADD Antikörper

FADD Reaktivität: Maus, Ratte WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7259174
  • Target Alle FADD Antikörper anzeigen
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Reaktivität
    • 91
    • 60
    • 19
    • 17
    • 15
    Maus, Ratte
    Wirt
    • 97
    • 21
    Kaninchen
    Klonalität
    • 93
    • 25
    Polyklonal
    Konjugat
    • 70
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FADD Antikörper ist unkonjugiert
    Applikation
    • 92
    • 51
    • 33
    • 15
    • 15
    • 15
    • 15
    • 10
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant protein of human FADD
    Isotyp
    IgG
    Top Product
    Discover our top product FADD Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000 IF 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Andere Bezeichnung
    FADD (FADD Produkte)
    Synonyme
    MORT1 antikoerper, Mort1/FADD antikoerper, Mort1 antikoerper, TNFRSF6 antikoerper, adaptor antikoerper, fadd antikoerper, mort1 antikoerper, xfadd antikoerper, Fas associated via death domain antikoerper, Fas (TNFRSF6)-associated via death domain antikoerper, Fas associated via death domain S homeolog antikoerper, Fas (tnfrsf6)-associated via death domain antikoerper, FADD antikoerper, Fadd antikoerper, fadd.S antikoerper, fadd antikoerper
    Hintergrund
    The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
    Molekulargewicht

    Observed_MW: 27 kDa

    Calculated_MW: 23 kDa

    Gen-ID
    8772
    UniProt
    Q13158
    Pathways
    Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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