FADD Antikörper (AA 20-150)
Kurzübersicht für FADD Antikörper (AA 20-150) (ABIN7193411)
Target
Alle FADD Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 20-150
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Verwendungszweck
- FADD Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Purified recombinant fragment of human FADD (AA: 20-150) expressed in E. Coli.
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Isotyp
- IgG1
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anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibody
FADD Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 12-206) antibodyFADD Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 7-178) antibodyFADD Reaktivität: Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibodyFADD Reaktivität: Maus WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD Reaktivität: Human WB, IHC, ELISA, IF, ICC Wirt: Maus Monoclonal J1D2 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 109-208) antibodyFADD Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3C3 unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208) antibodyFADD Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 94-208) antibodyFADD Reaktivität: Human WB, IHC, IP, IF Wirt: Maus Monoclonal 1-FADD unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (C-Term) antibodyFADD Reaktivität: Maus, Ratte WB, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 106-135) antibodyFADD Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB40884 unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
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Andere Bezeichnung
- FADD
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Hintergrund
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The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. [provided by RefSeq, Jul 2008]
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Molekulargewicht
- 23.3 kDa
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Gen-ID
- 8772
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UniProt
- Q13158
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Pathways
- Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
Target
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