BAD Antikörper
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- Target Alle BAD Antikörper anzeigen
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BAD Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide of human BAD (NP_004313.1).
- Isotyp
- IgG
- Top Product
- Discover our top product BAD Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:200 IF 1:10-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- BAD (BCL2-Associated Agonist of Cell Death (BAD))
- Andere Bezeichnung
- BAD (BAD Produkte)
- Synonyme
- bad antikoerper, fa01b12 antikoerper, wu:fa01b12 antikoerper, wu:fa96d04 antikoerper, BAD antikoerper, BBC2 antikoerper, BCL2L8 antikoerper, AI325008 antikoerper, Bbc2 antikoerper, BCL2-associated agonist of cell death b antikoerper, BCL2 associated agonist of cell death antikoerper, BCL2-associated agonist of cell death antikoerper, badb antikoerper, BAD antikoerper, Bad antikoerper
- Hintergrund
- The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
- Molekulargewicht
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Observed_MW: 16kDa
Calculated_MW: 18kDa
- Gen-ID
- 572
- UniProt
- Q92934
- Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
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