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BAD Produkte

(BCL2-Associated Agonist of Cell Death (BAD))

Kategorien

The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008].

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Ausgewählte BAD Kategorien

BAD Antikörper

High quality antibodies with extensive validation data.

BAD ELISA Kits

Reliable ELISA kits for a wide range of species.

BAD Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene BAD Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC (p), IF (p), IF (cc), FACS, ICC, IHC (fro)
Validierungen
  • (3)
  • (1)
Kat. Nr. ABIN674709
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, ICC, IP
Validierungen
  • (8)
Kat. Nr. ABIN7443224
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, FACS
Validierungen
  • (5)
Kat. Nr. ABIN5542486
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene BAD ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965132
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965131
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965127
Menge 96 tests
Datenblatt Datenblatt

Empfohlene BAD Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346356
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1775808
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Insect Cells
Validierungen
  • (1)
Kat. Nr. ABIN3122934
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren BAD Produkten

Mega Tiber, Kocyigit Sevinc, Kilinc, Orun: "Biological effects of whole Z.Officinale extract on chronic myeloid leukemia cell line K562." in: Gene, Vol. 692, pp. 217-222, (2019) (PubMed).

Lu, Zhang, Tan, Luo, Zhao, Ma, Liang, Tan: "GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia." in: International journal of molecular medicine, Vol. 38, Issue 1, pp. 105-12, (2017) (PubMed).

Hu, Kuo, Senadi, Chang, Wang: "Photodynamic Therapy Using Indolines-Fused-Triazoles Induces Mitochondrial Apoptosis in Human Non-Melanoma BCC Cells." in: Anticancer research, Vol. 37, Issue 10, pp. 5499-5505, (2017) (PubMed).

Mishra, Thakur, Somal, Parmar, Yadav, Bharati, Bharti, Paul, Verma, Chouhan, Sharma, Singh, González, DOcchio, Sarkar et al.: "Expression and localization of angiopoietin family in buffalo ovarian follicles during different stages of development and modulatory role of angiopoietins on steroidogenesis and survival of cultured ..." in: Theriogenology, Vol. 86, Issue 7, pp. 1818-33, (2016) (PubMed).

Mishra, Parmar, Yadav, Reshma, Bharati, Bharti, Paul, Chouhan, Taru Sharma, Singh, Sarkar et al.: "Expression and localization of angiopoietin family in corpus luteum during different stages of oestrous cycle and modulatory role of angiopoietins on steroidogenesis, angiogenesis and survivability ..." in: Reproduction in domestic animals = Zuchthygiene, Vol. 51, Issue 6, pp. 855-869, (2016) (PubMed).

Shan, Yan, Diao, Lin, Wang, Zhang, Zhang, Wei: "Involvement of caspases and their upstream regulators in myocardial apoptosis in a rat model of selenium deficiency-induced dilated cardiomyopathy." in: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), Vol. 31, pp. 85-91, (2015) (PubMed).

Liu, Chen, Chau, Jan, Chen, Hsu, Lin, Juang, Lu, Cheng, Chen, Chang, Ting, Kao, Hsiao, Huang: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." in: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).

Huang, Liu, Chen, Zeng, Wang, Zhang, Mo, Li: "Loss of Bad expression confers poor prognosis in non-small cell lung cancer." in: Medical oncology (Northwood, London, England), Vol. 29, Issue 3, pp. 1648-55, (2012) (PubMed).

Gan, Chen, Zhong, Wang, Lam, Liu, Zhang, Zhou, Yu, Si, Wang, Jin: "ZIC1 is downregulated through promoter hypermethylation, and functions as a tumor suppressor gene in colorectal cancer." in: PLoS ONE, Vol. 6, Issue 2, pp. e16916, (2011) (PubMed).

Polzien, Baljuls, Albrecht, Hekman, Rapp: "BAD contributes to RAF-mediated proliferation and cooperates with B-RAF-V600E in cancer signaling." in: The Journal of biological chemistry, Vol. 286, Issue 20, pp. 17934-44, (2011) (PubMed).

Synonyme und alternative Namen zu BAD

BCL2-associated agonist of cell death b (badb), BCL2 associated agonist of cell death (BAD), BCL2-associated agonist of cell death (Bad), AI325008, bad, BAD, BBC2, Bbc2, BCL2L8, fa01b12, wu:fa01b12, wu:fa96d04

Bezeichner auf Proteinebene für BAD

  • proapoptotic BH3-only protein
  • BCL2-antagonist of cell death
  • BCL2-associated agonist of cell death
  • BCL-X/BCL-2 binding protein
  • BCL2-antagonist of cell death protein
  • BCL2-binding component 6
  • BCL2-binding protein
  • bcl-2-binding component 6
  • bcl-2-like protein 8
  • bcl-XL/Bcl-2-associated death promoter
  • bcl2 antagonist of cell death
  • bcl2-L-8
  • Bcl-associated death promoter
  • bcl-xL/Bcl-2-associated death promoter
  • Bcl2-antagonist of cell death
  • bcl-2 associated death agonist
  • bcl2-associated death promoter
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