IL-1 beta Antikörper (AA 124-223)
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- Target Alle IL-1 beta (IL1B) Antikörper anzeigen
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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Bindungsspezifität
- AA 124-223
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL-1 beta Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- CTLRDSQQKS LVMSGPYELK ALHLQGQDME QQVVFSMSFV QGEESNDKIP VALGLKEKNL YLSCVLKDDK PTLQLESVDP KNYPKKKMEK RFVFNKIEIN
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 124-223 of human IL1beta (NP_000567.1).
- Isotyp
- IgG
- Top Product
- Discover our top product IL1B Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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Phloretin attenuates hyperuricemia-induced endothelial dysfunction through co-inhibiting inflammation and GLUT9-mediated uric acid uptake." in: Journal of cellular and molecular medicine, Vol. 21, Issue 10, pp. 2553-2562, (2018) (PubMed).
: "Dexmedetomidine protects against lipopolysaccharide-induced sepsis-associated acute kidney injury via an α7 nAChR-dependent pathway." in: Biomedicine & pharmacotherapy, Vol. 106, pp. 210-216, (2018) (PubMed).
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Phloretin attenuates hyperuricemia-induced endothelial dysfunction through co-inhibiting inflammation and GLUT9-mediated uric acid uptake." in: Journal of cellular and molecular medicine, Vol. 21, Issue 10, pp. 2553-2562, (2018) (PubMed).
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- Target
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- Andere Bezeichnung
- IL1B (IL1B Produkte)
- Synonyme
- IL-1 antikoerper, IL1-BETA antikoerper, IL1F2 antikoerper, IL-1BETA antikoerper, IL1beta antikoerper, il1-b antikoerper, zgc:111873 antikoerper, IL-1B antikoerper, IL-1beta antikoerper, Il-1b antikoerper, IL1B antikoerper, IL-1 beta antikoerper, IL-1b antikoerper, interleukin 1 beta antikoerper, interleukin 1, beta antikoerper, IL1B antikoerper, il1b antikoerper, Il1b antikoerper
- Hintergrund
- The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.,IL-1,IL1-BETA,IL1F2,IL1 beta,IL1B,Cell Biology & Developmental Biology,Apoptosis,Growth factor,Endocrine & Metabolism,Endocrine and metabolic diseases,Obesity,Immunology & Inflammation,Cytokines,Interleukins,NF-kB Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Cardiovascular,IL1B
- Molekulargewicht
- 30 kDa
- Gen-ID
- 3553
- UniProt
- P01584
- Pathways
- NF-kappaB Signalweg, Interferon-gamma Pathway, TLR Signalweg, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagie, Cancer Immune Checkpoints, Inflammasome
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