BRAF Antikörper (AA 280-460)
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- Target Alle BRAF Antikörper anzeigen
- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
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Bindungsspezifität
- AA 280-460
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BRAF Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- CVNYDQLDLL FVSKFFEHHP IPQEEASLAE TALTSGSSPS APASDSIGPQ ILTSPSPSKS IPIPQPFRPA DEDHRNQFGQ RDRSSSAPNV HINTIEPVNI DDLIRDQGFR GDGGSTTGLS ATPPASLPGS LTNVKALQKS PGPQRERKSS SSSEDRNRMK TLGRRDSSDD WEIPDGQITV G
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 280-460 of human B-Raf (NP_004324.2).
- Isotyp
- IgG
- Top Product
- Discover our top product BRAF Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
- Andere Bezeichnung
- BRAF (BRAF Produkte)
- Synonyme
- B-RAF1 antikoerper, BRAF1 antikoerper, NS7 antikoerper, RAFB1 antikoerper, C-RMIL antikoerper, RMIL antikoerper, B-Raf antikoerper, braf1 antikoerper, rafb1 antikoerper, b-raf1 antikoerper, sierrabraf antikoerper, BRAF antikoerper, 9930012E13Rik antikoerper, AA120551 antikoerper, AA387315 antikoerper, AA473386 antikoerper, B-raf antikoerper, Braf-2 antikoerper, Braf2 antikoerper, C230098H17 antikoerper, C87398 antikoerper, D6Ertd631e antikoerper, braf antikoerper, fc48g01 antikoerper, wu:fc48g01 antikoerper, B-Raf proto-oncogene, serine/threonine kinase antikoerper, B-Raf proto-oncogene, serine/threonine kinase S homeolog antikoerper, Braf transforming gene antikoerper, si:dkey-222f8.3 antikoerper, BRAF antikoerper, Braf antikoerper, braf.S antikoerper, braf antikoerper, si:dkey-222f8.3 antikoerper
- Hintergrund
- This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.,BRAF,B-RAF1,B-raf,BRAF1,NS7,RAFB1,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,Tyrosine kinases,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Cell Cycle,Cell differentiation,ESC Pluripotency and Differentiation,Immunology & Inflammation,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Neuroscience,BRAF
- Molekulargewicht
- 84 kDa
- Gen-ID
- 673
- UniProt
- P15056
- Pathways
- MAPK Signalweg, RTK Signalweg, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagie
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