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HRAS Antikörper (C-Term)
HRAS
Reaktivität: Human, Maus, Ratte
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5690065
Produktdetails anti-HRAS Antikörper
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Target
Alle HRAS Antikörper anzeigen
HRAS
(HRas proto-oncogene, GTPase (HRAS))
Bindungsspezifität
Alle Epitope für HRAS Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für HRAS Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für HRAS Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für HRAS Antikörper
Polyklonal
Konjugat
Alle Konjugate für HRAS Antikörper
Dieser HRAS Antikörper ist unkonjugiert
Applikation
Alle Applikationen für HRAS Antikörper
Western Blotting (WB), ELISA
Spezifität
N-RAS antibody is predicted to not cross-react with H-RAS
Aufreinigung
N-RAS Antibody is affinity chromatography purified via peptide column.
Immunogen
N-RAS antibody was raised against a 15 amino acid peptide near the carboxy terminus of human N-RAS. The immunogen is located within the last 50 amino acids of N-RAS.
Isotyp
IgG
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Discover our top product HRAS Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
N-RAS antibody can be used for detection of N-RAS by Western blot at 1 and 2 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
N-RAS Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
N-RAS antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Details zu HRAS
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Target
HRAS
(HRas proto-oncogene, GTPase (HRAS))
Andere Bezeichnung
N-RAS (HRAS Produkte )
Synonyme
C-BAS/HAS antikoerper, C-H-RAS antikoerper, C-HA-RAS1 antikoerper, CTLO antikoerper, H-RASIDX antikoerper, HAMSV antikoerper, HRAS1 antikoerper, K-RAS antikoerper, N-RAS antikoerper, RASH1 antikoerper, hras antikoerper, zgc:110250 antikoerper, HRAS antikoerper, H-RAS antikoerper, c-H-ras antikoerper, H-Ras antikoerper, K-Ras antikoerper, hras1 antikoerper, rash1 antikoerper, ras antikoerper, N-Ras antikoerper, c-bas/has antikoerper, H-ras antikoerper, Ha-ras antikoerper, Harvey-ras antikoerper, Hras-1 antikoerper, Kras2 antikoerper, c-Ha-ras antikoerper, c-rasHa antikoerper, hrasl antikoerper, zgc:110734 antikoerper, HRas proto-oncogene, GTPase antikoerper, v-Ha-ras Harvey rat sarcoma viral oncogene homolog a antikoerper, neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene antikoerper, Harvey rat sarcoma viral oncogene homolog L homeolog antikoerper, Harvey rat sarcoma viral oncogene homolog antikoerper, Harvey rat sarcoma virus oncogene antikoerper, NRAS proto-oncogene, GTPase antikoerper, -Ha-ras Harvey rat sarcoma viral oncogene homolog b antikoerper, HRAS antikoerper, hrasa antikoerper, LOC733587 antikoerper, Hras antikoerper, hras.L antikoerper, hras antikoerper, NRAS antikoerper, hrasb antikoerper
Hintergrund
N-RAS Antibody: Activating mutations and overexpression of classical Ras subfamily members (N-RAS, H-RAS, and K-RAS) have been widely investigated as key events in the development of human cancers. The N-RAS protein shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. N-RAS, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
Molekulargewicht
Predicted: 22 kDa Observed: 22 kDa
Gen-ID
4893
NCBI Accession
NP_002515
UniProt
P01111
Pathways
p53 Signalweg , MAPK Signalweg , RTK Signalweg , Fc-epsilon Rezeptor Signalübertragung , EGFR Signaling Pathway , Neurotrophin Signalübertragung , Hepatitis C , Autophagie , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , Regulation of long-term Neuronal Synaptic Plasticity , VEGF Signaling , BCR Signaling
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