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BRAF Antikörper (Middle Region)
BRAF
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5516469
Produktdetails anti-BRAF Antikörper
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Target
Alle BRAF Antikörper anzeigen
BRAF
(B-Raf proto-oncogene, serine/threonine kinase (BRAF))
Bindungsspezifität
Alle Epitope für BRAF Antikörper
Middle Region
Reaktivität
Alle Reaktivitäten für BRAF Antikörper
Human
Wirt
Alle Wirte für BRAF Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für BRAF Antikörper
Polyklonal
Konjugat
Alle Konjugate für BRAF Antikörper
Dieser BRAF Antikörper ist unkonjugiert
Applikation
Alle Applikationen für BRAF Antikörper
Western Blotting (WB)
Sequenz
PIPQPFRPAD EDHRNQFGQR DRSSSAPNVH INTIEPVNID DLIRDQGFRG
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human BRAF
Top Product
Discover our top product BRAF Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 16 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu BRAF
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Target
BRAF
(B-Raf proto-oncogene, serine/threonine kinase (BRAF))
Andere Bezeichnung
BRAF (BRAF Produkte )
Synonyme
B-RAF1 antikoerper, BRAF1 antikoerper, NS7 antikoerper, RAFB1 antikoerper, C-RMIL antikoerper, RMIL antikoerper, B-Raf antikoerper, braf1 antikoerper, rafb1 antikoerper, b-raf1 antikoerper, sierrabraf antikoerper, BRAF antikoerper, 9930012E13Rik antikoerper, AA120551 antikoerper, AA387315 antikoerper, AA473386 antikoerper, B-raf antikoerper, Braf-2 antikoerper, Braf2 antikoerper, C230098H17 antikoerper, C87398 antikoerper, D6Ertd631e antikoerper, braf antikoerper, fc48g01 antikoerper, wu:fc48g01 antikoerper, B-Raf proto-oncogene, serine/threonine kinase antikoerper, B-Raf proto-oncogene, serine/threonine kinase S homeolog antikoerper, Braf transforming gene antikoerper, si:dkey-222f8.3 antikoerper, BRAF antikoerper, Braf antikoerper, braf.S antikoerper, braf antikoerper, si:dkey-222f8.3 antikoerper
Hintergrund
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. Alias Symbols: NS7, BRAF1, RAFB1, B-RAF1 Protein Size: 766
Gen-ID
673
NCBI Accession
NM_004333 , NP_004324
UniProt
P15056
Pathways
MAPK Signalweg , RTK Signalweg , Neurotrophin Signalübertragung , Ribonucleoprotein Complex Subunit Organization , Hepatitis C , Autophagie
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