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eIF4EBP1 Antikörper (C-Term)
EIF4EBP1
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5514474
Produktdetails anti-eIF4EBP1 Antikörper
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Target
Alle eIF4EBP1 (EIF4EBP1) Antikörper anzeigen
eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Bindungsspezifität
Alle Epitope für eIF4EBP1 Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für eIF4EBP1 Antikörper
Human
Wirt
Alle Wirte für eIF4EBP1 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für eIF4EBP1 Antikörper
Polyklonal
Konjugat
Alle Konjugate für eIF4EBP1 Antikörper
Dieser eIF4EBP1 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für eIF4EBP1 Antikörper
Western Blotting (WB)
Sequenz
NSPVTKTPPR DLPTIPGVTS PSSDEPPMEA SQSHLRNSPE DKRAGGEESQ
Produktmerkmale
This is a rabbit polyclonal antibody against 4EBP1. It was validated on Western Blot.
Aufreinigung
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human 4EBP1
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Discover our top product EIF4EBP1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu eIF4EBP1
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Target
eIF4EBP1 (EIF4EBP1)
(Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
Andere Bezeichnung
4EBP1 (EIF4EBP1 Produkte )
Synonyme
4E-BP1 antikoerper, 4EBP1 antikoerper, BP-1 antikoerper, PHAS-I antikoerper, 4e-bp1 antikoerper, AA959816 antikoerper, 153432_at antikoerper, 43-BP antikoerper, 4E-BP antikoerper, 4EBP antikoerper, 4e-bp antikoerper, 4eBP antikoerper, 4ebp antikoerper, BcDNA.HL08053 antikoerper, BcDNA:HL08053 antikoerper, CG8846 antikoerper, CT8705 antikoerper, Dm 4E-BP antikoerper, Dmel\\CG8846 antikoerper, Phas1 antikoerper, Thor/EIF4EBP antikoerper, anon-WO0172774.158 antikoerper, d4E-BP antikoerper, d4E-BP1 antikoerper, d4EBP antikoerper, d4e-bp antikoerper, d4eBP antikoerper, dthor antikoerper, eIF4E-BP antikoerper, l(2)06270 antikoerper, l(2)k07736 antikoerper, l(2)k13517 antikoerper, pp20 antikoerper, thor antikoerper, EIF4EBP1 antikoerper, fc04h09 antikoerper, wu:fc04h09 antikoerper, zgc:64137 antikoerper, eukaryotic translation initiation factor 4E binding protein 1 antikoerper, CG8846 gene product from transcript CG8846-RA antikoerper, EIF4EBP1 antikoerper, Eif4ebp1 antikoerper, Thor antikoerper, eif4ebp1 antikoerper
Hintergrund
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. Alias Symbols: EIF4EBP1, Protein Interaction Partner: Mtor, MLST8, RPTOR, TCF4, REL, EIF4E, RICTOR, MAPKAP1, UBC, SLMAP, LATS1, PRKDC, ATM, PPP2R4, STK3, MAPK14, LRRK2, AGO2, MAPK1, KLHL25, IRAK4, PRKCA, GSK3B, CHTF8, RHEBL1, RPS6KB1, MAPKAPK5, PPP2CA, RPS6KA5, EIF4E2, MVD, RORC, BUB1, AKT1, CSNK2A2, CSNK2A1 Protein Size: 118
Gen-ID
1978
NCBI Accession
NP_004086
UniProt
Q13541
Pathways
MAPK Signalweg , PI3K-Akt Signalweg , RTK Signalweg , AMPK Signaling , Regulation of Cell Size , BCR Signaling
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