eIF4EBP1 Antikörper (pSer65)
Kurzübersicht für eIF4EBP1 Antikörper (pSer65) (ABIN5611114)
Target
Alle eIF4EBP1 (EIF4EBP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pSer65
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Verwendungszweck
- Phospho-4E-BP1 (Ser65) Antibody
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Aufreinigung
- Purified antibody
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Immunogen
- Synthesized peptide of human Phospho-4E-BP1 (Ser65).
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Isotyp
- IgG1
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anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr46) antibody
KD Validated EIF4EBP1 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 24GB4405 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pThr37), (pThr46) antibodyEIF4EBP1 Reaktivität: Human WB, IHC (p), IF (cc), IF (p), FACS, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (C-Term) antibodyEIF4EBP1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) antibodyKD Validated EIF4EBP1 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 24GB4410 unconjugated Recombinant Antibody
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 1-118) antibodyEIF4EBP1 Reaktivität: Human ELISA, IF, PLA Wirt: Maus Monoclonal 4F3-H2 unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pSer65) antibodyEIF4EBP1 Reaktivität: Maus WB, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 101-118) antibodyEIF4EBP1 Reaktivität: Human, Maus, Ratte, Kaninchen, Hamster WB, IHC, IHC (p), EMSA Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (C-Term) antibodyEIF4EBP1 Reaktivität: Human, Maus IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (pSer65), (pThr70) antibodyEIF4EBP1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) (AA 2-118) antibodyEIF4EBP1 Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100 - 1/500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
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Andere Bezeichnung
- 4E-BP1
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Hintergrund
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This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
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Molekulargewicht
- 12.6 kDa
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Gen-ID
- 1978
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UniProt
- Q13541
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Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, BCR Signaling
Target
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