BRAF Antikörper (pThr598)

Produktnummer ABIN548622

Produktdetails anti-BRAF Antikörper

Target: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Bindungsspezifität: pThr598

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRAF Antikörper ist unkonjugiert

Applikation: ELISA, Dot Blot (DB)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphopeptide of BRAF.

Kreuzreaktivität: Human

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding T598 of human BRAF.

Anwendungsinformationen

Applikationshinweise: ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide).

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 2 weeks. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-BRAF Antikörper (ABIN548622)

Yamaguchi, Wallace, Magenheimer, Hempson, Grantham, Calvet: "Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype." in: The Journal of biological chemistry, Vol. 279, Issue 39, pp. 40419-30, (2004) (PubMed).

Frattini, Ferrario, Bressan, Balestra, De Cecco, Mondellini, Bongarzone, Collini, Gariboldi, Pilotti, Pierotti, Greco: "Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer." in: Oncogene, Vol. 23, Issue 44, pp. 7436-40, (2004) (PubMed).

Loewe, Kittler, Fischer, Faé, Wolff, Petzelbauer: "BRAF kinase gene V599E mutation in growing melanocytic lesions." in: The Journal of investigative dermatology, Vol. 123, Issue 4, pp. 733-6, (2004) (PubMed).

Details zu BRAF

Target: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Andere Bezeichnung: B-Raf proto-oncogene (BRAF Produkte)

Synonyme: B-RAF1 antikoerper, BRAF1 antikoerper, NS7 antikoerper, RAFB1 antikoerper, C-RMIL antikoerper, RMIL antikoerper, B-Raf antikoerper, braf1 antikoerper, rafb1 antikoerper, b-raf1 antikoerper, sierrabraf antikoerper, BRAF antikoerper, 9930012E13Rik antikoerper, AA120551 antikoerper, AA387315 antikoerper, AA473386 antikoerper, B-raf antikoerper, Braf-2 antikoerper, Braf2 antikoerper, C230098H17 antikoerper, C87398 antikoerper, D6Ertd631e antikoerper, braf antikoerper, fc48g01 antikoerper, wu:fc48g01 antikoerper, B-Raf proto-oncogene, serine/threonine kinase antikoerper, B-Raf proto-oncogene, serine/threonine kinase S homeolog antikoerper, Braf transforming gene antikoerper, si:dkey-222f8.3 antikoerper, BRAF antikoerper, Braf antikoerper, braf.S antikoerper, braf antikoerper, si:dkey-222f8.3 antikoerper

Gen-ID: 673

Pathways: MAPK Signalweg, RTK Signalweg, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagie