BRAF Antikörper (N-Term)

Produktnummer ABIN548428

Produktdetails anti-BRAF Antikörper

Target: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRAF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of BRAF .

Spezifität: This sequence has high homology with similar regions in rat and mouse B-Raf, and has low homology to other Raf family members.

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human BRAF .

Anwendungsinformationen

Applikationshinweise: ELISA (1:2000)
Western Blot (1:500)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-BRAF Antikörper (ABIN548428)

Brummer, Martin, Herzog, Misawa, Daly, Reth: "Functional analysis of the regulatory requirements of B-Raf and the B-Raf(V600E) oncoprotein." in: Oncogene, Vol. 25, Issue 47, pp. 6262-76, (2006) (PubMed).

Karbowniczek, Robertson, Henske: "Rheb inhibits C-raf activity and B-raf/C-raf heterodimerization." in: The Journal of biological chemistry, Vol. 281, Issue 35, pp. 25447-56, (2006) (PubMed).

Wilhelm, Carter, Tang, Wilkie, McNabola, Rong, Chen, Zhang, Vincent, McHugh, Cao, Shujath, Gawlak, Eveleigh, Rowley, Liu, Adnane, Lynch, Auclair, Taylor, Gedrich, Voznesensky, Riedl, Post, Bollag et al.: "BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis. ..." in: Cancer research, Vol. 64, Issue 19, pp. 7099-109, (2004) (PubMed).

Details zu BRAF

Target: BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))

Andere Bezeichnung: B-Raf proto-oncogene (BRAF Produkte)

Synonyme: B-RAF1 antikoerper, BRAF1 antikoerper, NS7 antikoerper, RAFB1 antikoerper, C-RMIL antikoerper, RMIL antikoerper, B-Raf antikoerper, braf1 antikoerper, rafb1 antikoerper, b-raf1 antikoerper, sierrabraf antikoerper, BRAF antikoerper, 9930012E13Rik antikoerper, AA120551 antikoerper, AA387315 antikoerper, AA473386 antikoerper, B-raf antikoerper, Braf-2 antikoerper, Braf2 antikoerper, C230098H17 antikoerper, C87398 antikoerper, D6Ertd631e antikoerper, braf antikoerper, fc48g01 antikoerper, wu:fc48g01 antikoerper, B-Raf proto-oncogene, serine/threonine kinase antikoerper, B-Raf proto-oncogene, serine/threonine kinase S homeolog antikoerper, Braf transforming gene antikoerper, si:dkey-222f8.3 antikoerper, BRAF antikoerper, Braf antikoerper, braf.S antikoerper, braf antikoerper, si:dkey-222f8.3 antikoerper

Gen-ID: 673

Pathways: MAPK Signalweg, RTK Signalweg, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagie