TCF3 Antikörper (N-Term)

Produktnummer ABIN500879

Produktdetails anti-TCF3 Antikörper

Target: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Peptide affinity chromatography

Immunogen: TCF3 antibody was raised against a 17 amino acid peptide near the amino terminus of human TCF3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu TCF3

Target: TCF3 (Transcription Factor 3 (E2A Immunoglobulin Enhancer Binding Factors E12/E47) (TCF3))

Andere Bezeichnung: TCF3 / E2A (TCF3 Produkte)

Synonyme: E2A antikoerper, E47 antikoerper, ITF1 antikoerper, TCF-3 antikoerper, VDIR antikoerper, bHLHb21 antikoerper, tcf3a antikoerper, zgc:113045 antikoerper, A1 antikoerper, AA408400 antikoerper, ALF2 antikoerper, AW209082 antikoerper, E12 antikoerper, E12/E47 antikoerper, ME2 antikoerper, Pan1 antikoerper, Pan2 antikoerper, Tcfe2a antikoerper, bhlhb21 antikoerper, e2a antikoerper, itf1 antikoerper, tcfe2a antikoerper, vdir antikoerper, xtcf-3 antikoerper, xtcf3 antikoerper, G12 antikoerper, TCF7L1 antikoerper, XE3 antikoerper, transcription factor 3 antikoerper, transcription factor 3b antikoerper, transcription factor 3 L homeolog antikoerper, transcription factor E2a antikoerper, TCF3 antikoerper, tcf3b antikoerper, Tcf3 antikoerper, tcf3.L antikoerper, tcfe2a antikoerper

Hintergrund: The TCF3 gene, also called E2A, encodes two basic helix-loop-helix (bHLH) transcription factors, E12 and E47, through alternative splicing. These transcription factors are involved in mediating canonical Wnt signaling, which is very important in a diverse array of cellular functions such as stem cell proliferation, self-renewal, activation, fate determination, differentiation and aging and senescence. They bind beta-catenin and can act as transcriptional activators or repressors for Wnt target genes, and have been shown to regulate specific target genes during CNS development downstream of Wnt signaling. TCF3/Lef complexes are also known to play key roles in controlling cell fate lineages in multipotent skin stem cells.Synonyms: ITF-1, ITF1, Immunoglobulin enhancer-binding factor E12/E47, Immunoglobulin transcription factor 1, Kappa-E2-binding factor, TCF-3, Transcription factor 3, Transcription factor E2-alpha, Transcription factor ITF-1

Gen-ID: 6929

NCBI Accession: NP_003191

Pathways: WNT Signalweg, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Production of Molecular Mediator of Immune Response